ERCC1 and ERCC4

  • Data Source:
  • HPRD (in vitro, in vivo)

ERCC1

ERCC4

Description ERCC excision repair 1, endonuclease non-catalytic subunit ERCC excision repair 4, endonuclease catalytic subunit
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease or HDL levels (pleiotropy) ( 30805717)
  • Body mass index ( 26426971)
  • Body mass index (age>50) ( 26426971)
  • Body mass index x age interaction ( 26426971)
  • Body mass index x sex x age interaction (4df test) ( 26426971)
  • Simvastatin-induced myopathy ( 31220337)
Interacting Genes 18 interacting genes: APP CHRM5 ERCC4 GAS8 KIF11 MKRN3 RAD52 RPA1 RPA2 RPA3 SLX1A TRMT2B UBL7 UHRF1 USHBP1 USP45 VPS37B XPA 13 interacting genes: ERCC1 FANCG GTF2H1 KIF11 RAD52 RPA1 RPA2 SLX1A SLX4 SPTAN1 SUMO2 TACC1 XPA
Entrez ID 2067 2072
HPRD ID 00533 00594
Ensembl ID ENSG00000012061 ENSG00000175595
Uniprot IDs A0A024R0Q6 P07992 A0A1W1GSK9 B4DXD8 Q92889
PDB IDs 1Z00 2A1I 2A1J 2JNW 2JPD 2MUT 6SXA 6SXB 1Z00 2A1J 2AQ0 2KN7 2MUT 6SXA 6SXB
Enriched GO Terms of Interacting Partners?
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