ENSA and RAP2A

Data Source:
BioGRID (two hybrid)

		ENSA	RAP2A
Description		endosulfine alpha	RAP2A, member of RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm	Cytosol Plasma Membrane Midbody Recycling Endosome Recycling Endosome Membrane
	Molecular Function	Protein Phosphatase Inhibitor Activity Signaling Receptor Binding Protein Binding Ion Channel Inhibitor Activity Phosphatase Inhibitor Activity Potassium Channel Inhibitor Activity Protein Phosphatase Regulator Activity Protein Phosphatase 2A Binding	Magnesium Ion Binding GTPase Activity Protein Binding GTP Binding GDP Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Response To Nutrient Negative Regulation Of Phosphoprotein Phosphatase Activity Negative Regulation Of Protein Dephosphorylation Regulation Of Insulin Secretion Cell Division	Positive Regulation Of Protein Phosphorylation Microvillus Assembly Negative Regulation Of Cell Migration Actin Cytoskeleton Reorganization Positive Regulation Of Protein Autophosphorylation Rap Protein Signal Transduction Cellular Protein Localization Cellular Response To Drug Establishment Of Protein Localization Establishment Of Epithelial Cell Apical/basal Polarity Regulation Of JNK Cascade Regulation Of Dendrite Morphogenesis Protein Localization To Plasma Membrane
Pathways		MASTL Facilitates Mitotic Progression MASTL Facilitates Mitotic Progression
Drugs			Guanosine-5'-Triphosphate Guanosine-5'-Diphosphate
Diseases
GWAS		Albumin-globulin ratio ( 29403010) Chronotype ( 30696823) Coffee consumption ( 31959922) Eosinophil counts ( 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Granulocyte percentage of myeloid white cells ( 27863252) Lung function (FEV1) ( 26635082) Lung function (FVC) ( 26635082) Mean corpuscular volume ( 32888494) Monocyte count ( 29403010 27863252) Monocyte percentage of white cells ( 32888494 27863252) Morning person ( 30696823) Neutrophil percentage of granulocytes ( 27863252) Non-albumin protein levels ( 29403010) Pericardial adipose tissue adjusted for height and weight ( 27918534) Refractive error ( 32231278) Rhegmatogenous retinal detachment ( 23585552) Sum eosinophil basophil counts ( 27863252) Urate levels ( 31578528)	Gut microbiota (bacterial taxa) ( 27723756) Peripheral artery disease ( 26488411)
Interacting Genes		10 interacting genes: ABCC8 ACD ARIH2 ENO2 KCTD15 POT1 PSEN1 RAP2A SNCA SRPK2	32 interacting genes: ACVR1 AFDN ARHGAP29 BMPR1B EEF1A1 ENSA FKBP2 FNTB FTL GABARAPL2 GRIN1 GRIN2D MAP4K4 NEDD4 PLG RAF1 RALGDS RAPGEF3 RAPGEF4 RAPGEF5 RAPGEF6 RASIP1 RASSF5 RGL1 RGS14 RRP9 RUNDC3A SERPINA1 SMAD1 TGFBR1 TM7SF2 TNIK
Entrez ID		2029	5911
HPRD ID		11927	01547
Ensembl ID		ENSG00000143420	ENSG00000125249
Uniprot IDs		O43768	P10114
PDB IDs			1KAO 2RAP 3RAP
Enriched GO Terms of Interacting Partners?
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