TRDMT1 and SNRPD3

Data Source:
BioGRID (two hybrid)

		TRDMT1	SNRPD3
Description		tRNA aspartic acid methyltransferase 1	small nuclear ribonucleoprotein D3 polypeptide
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm	Commitment Complex Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP U7 SnRNP U1 SnRNP U2 SnRNP U4 SnRNP U12-type Spliceosomal Complex Telomerase Holoenzyme Complex Cytosol Nuclear Body Small Nuclear Ribonucleoprotein Complex Methylosome PICln-Sm Protein Complex SMN-Sm Protein Complex U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome U2-type Catalytic Step 2 Spliceosome Precatalytic Spliceosome Catalytic Step 2 Spliceosome Spliceosomal Tri-snRNP Complex
	Molecular Function	RNA Binding TRNA Methyltransferase Activity TRNA (cytosine-5-)-methyltransferase Activity	RNA Binding Protein Binding Enzyme Binding Telomerase RNA Binding Histone Pre-mRNA DCP Binding U7 SnRNA Binding
	Biological Process	Response To Amphetamine TRNA Modification TRNA Methylation TRNA Stabilization	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription Protein Methylation Histone MRNA Metabolic Process RNA Splicing Import Into Nucleus
Pathways		tRNA modification in the nucleus and cytosol	SLBP independent Processing of Histone Pre-mRNAs snRNP Assembly mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway RNA Polymerase II Transcription Termination SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
Drugs		Pentamidine S-adenosyl-L-homocysteine Glycerin
Diseases
GWAS		Platelet count ( 32888494) Platelet distribution width ( 32888494) Plateletcrit ( 32888494) Telomere length ( 24478790)	Acne (severe) ( 24927181) Gamma glutamyl transferase levels ( 32084209)
Interacting Genes		14 interacting genes: APP COPS6 DDX24 EEF1A1 GBE1 LRIF1 NFRKB RBM48 SETDB1 SNRPD3 STX1A TBC1D2B UNC119 UTP14A	27 interacting genes: CASP8 CLNS1A CRY1 DDX20 GEMIN2 GEMIN5 GEMIN6 GEMIN7 IL12RB1 IL7R LSM3 LSM7 NR1I3 NTAQ1 PRMT5 RBL1 SMN1 SMN2 SNRPB SNRPE SNRPG SREK1 STRAP STXBP2 STXBP3 TRDMT1 WDR77
Entrez ID		1787	6634
HPRD ID		16001	03039
Ensembl ID		ENSG00000107614	ENSG00000100028
Uniprot IDs		A0A0U1U562 B4DQZ2 O14717 Q6ICS7 Q7Z3E4	P62318
PDB IDs		1G55	1D3B 3CW1 3JCR 3PGW 3VRI 4PJO 4WZJ 5MQF 5O9Z 5XJC 5YZG 5Z56 5Z57 5Z58 6AH0 6AHD 6FF7 6ICZ 6ID0 6ID1 6QDV 6QW6 6QX9 6V4X 6Y53 6Y5Q 7A5P
Enriched GO Terms of Interacting Partners?
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