E2F3 and SRA1

Data Source:
BioGRID (far western blotting)

		E2F3	SRA1
Description		E2F transcription factor 3	steroid receptor RNA activator 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm RNA Polymerase II Transcription Regulator Complex	Nucleus Nucleoplasm Transcription Regulator Complex Cytoplasm Cytosol Plasma Membrane Microtubule Cytoskeleton SCAR Complex Cell Leading Edge Intercellular Bridge Ribonucleoprotein Complex
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Protein Dimerization Activity Sequence-specific Double-stranded DNA Binding	Steroid Receptor RNA Activator RNA Binding DNA Binding Transcription Coactivator Activity Protein Binding Nuclear Receptor Coactivator Activity
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Protein Import Into Nucleus Positive Regulation Of Cell Population Proliferation Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Fat Cell Proliferation Positive Regulation Of Vascular Associated Smooth Muscle Cell Apoptotic Process	Regulation Of Transcription By RNA Polymerase II Apoptotic Process Regulation Of Mitotic Cell Cycle Cell Differentiation Regulation Of Apoptotic Process Negative Regulation Of Myoblast Differentiation Positive Regulation Of Transcription, DNA-templated Cellular Response To Estrogen Stimulus
Pathways		Pre-NOTCH Transcription and Translation Pre-NOTCH Transcription and Translation Oxidative Stress Induced Senescence Oncogene Induced Senescence CDC6 association with the ORC:origin complex G2 Phase Cyclin D associated events in G1 Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)
Drugs
Diseases
GWAS		Adult body size ( 32376654) Estimated glomerular filtration rate in non-diabetics ( 31451708) Metabolite levels ( 23823483) Molybdenum levels ( 26025379) Obesity-related traits ( 23251661) Triglyceride levels ( 32203549)	Refractive error ( 32231278) Schizophrenia ( 28991256) Serum immune biomarker levels ( 32066700)
Interacting Genes		25 interacting genes: ATAD2 CCNA2 CDK3 CREBBP DNMT3L FHL2 FZR1 HCFC1 HELLS MGA MYBL2 PKIB RB1 RNF144A RYBP SP1 SPIB SRA1 TEAD3 TFDP1 TFDP2 TFE3 UCHL5 WNK1 YY1	30 interacting genes: ALX1 ATF1 ATF2 ATF3 ATF4 BLZF1 BTG2 CEBPA CREB1 DDIT3 DMTF1 E2F3 EGR1 EGR2 ESR1 ESR2 ESRRG ETS1 ETS2 FOS FOSB FOSL2 GATA1 GTF2B GTF2H2 GTF3C5 HAND1 NR3C1 TFAP2A UBE2Z
Entrez ID		1871	10011
HPRD ID		02693	18716
Ensembl ID		ENSG00000112242	ENSG00000213523
Uniprot IDs		O00716	Q9HD15
PDB IDs			2MGX 4NBO
Enriched GO Terms of Interacting Partners?
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