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RNF168 and ECPAS
Data Source:
BioGRID
(two hybrid)
RNF168
ECPAS
Description
ring finger protein 168
Ecm29 proteasome adaptor and scaffold
Image
No pdb structure
GO Annotations
Cellular Component
Ubiquitin Ligase Complex
Nucleus
Nucleoplasm
Cytosol
Protein-containing Complex
Site Of Double-strand Break
Proteasome Complex
Nucleus
Nucleoplasm
Early Endosome
Late Endosome
Multivesicular Body
Endoplasmic Reticulum
Endoplasmic Reticulum-Golgi Intermediate Compartment
Trans-Golgi Network
Centrosome
Membrane
COPII-coated ER To Golgi Transport Vesicle
Endocytic Vesicle
Cytoplasmic Vesicle
Molecular Function
Chromatin Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Nucleosome Binding
Histone Binding
Ubiquitin Binding
Metal Ion Binding
K63-linked Polyubiquitin Modification-dependent Protein Binding
Protein Binding
Molecular Adaptor Activity
Proteasome Binding
Biological Process
Double-strand Break Repair
Double-strand Break Repair Via Nonhomologous End Joining
Ubiquitin-dependent Protein Catabolic Process
Cellular Response To DNA Damage Stimulus
Response To Ionizing Radiation
Protein Ubiquitination
Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter
Histone H2A Monoubiquitination
Interstrand Cross-link Repair
Histone H2A-K13 Ubiquitination
Histone H2A-K15 Ubiquitination
Isotype Switching
Positive Regulation Of DNA Repair
Protein K63-linked Ubiquitination
Histone H2A K63-linked Ubiquitination
Ubiquitin-dependent ERAD Pathway
Proteasome Assembly
Pathways
SUMOylation of DNA damage response and repair proteins
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Nonhomologous End-Joining (NHEJ)
Processing of DNA double-strand break ends
G2/M DNA damage checkpoint
Drugs
Diseases
RIDDLE syndrome
GWAS
Fat distribution (HIV) (
21897333
)
Mean corpuscular hemoglobin (
32888494
)
Mean corpuscular volume (
32888494
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Triglyceride levels (
32203549
)
Interacting Genes
32 interacting genes:
ALAS1
ECPAS
H2AC13
H2AC18
H2AC20
H2AC4
H2AX
H2AZ1
H2BC21
JMJD1C
KDM1A
KDM4A
LAPTM5
PALB2
PARP1
RABGEF1
RNF11
RNF126
SQSTM1
SUMO2
TNFAIP3
TOP2A
TRIM8
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2E1
UBE2G2
UBE2L3
USP7
WBP2
36 interacting genes:
AGTRAP
ANK2
ANKRD17
BSND
CCDC57
CEP170B
CKS1B
CMTM5
CMTM6
CPD
DGAT2L6
DNAJB9
DST
FBXO2
GAREM2
GOLGB1
HNRNPM
HSD17B13
HSPB1
MAL2
MKI67
MYH10
PCM1
PCYT1B
PSMC3
RAB11FIP4
RNF168
SF3B2
SPECC1L
SYNE1
TNFRSF10D
UBE2G2
UBE2Q1
UIMC1
VPS11
ZNF483
Entrez ID
165918
23392
HPRD ID
08190
11078
Ensembl ID
ENSG00000163961
ENSG00000136813
Uniprot IDs
Q8IYW5
PDB IDs
3L11
4GB0
5XIS
5XIT
5XIU
5YDK
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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