ECPAS and MKI67

Data Source:
BioGRID (two hybrid)

		ECPAS	MKI67
Description		Ecm29 proteasome adaptor and scaffold	marker of proliferation Ki-67
Image		No pdb structure
GO Annotations	Cellular Component	Proteasome Complex Nucleus Nucleoplasm Early Endosome Late Endosome Multivesicular Body Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Trans-Golgi Network Centrosome Membrane COPII-coated ER To Golgi Transport Vesicle Endocytic Vesicle Cytoplasmic Vesicle	Condensed Chromosome Nucleus Nucleoplasm Chromosome Nucleolus Membrane Nuclear Body
	Molecular Function	Protein Binding Molecular Adaptor Activity Proteasome Binding	DNA Binding RNA Binding Protein Binding ATP Binding Protein C-terminus Binding
	Biological Process	Ubiquitin-dependent ERAD Pathway Proteasome Assembly	Cell Cycle Regulation Of Mitotic Nuclear Division Cell Population Proliferation Regulation Of Chromosome Segregation Regulation Of Chromatin Organization
Pathways
Drugs
Diseases
GWAS			Alzheimer's disease in APOE e4- carriers ( 25778476) Drug experimentation measurement ( 30718321) Lead levels ( 26025379) Select biomarker traits ( 17903293) Triglyceride levels x loop diuretics use interaction ( 31806883)
Interacting Genes		36 interacting genes: AGTRAP ANK2 ANKRD17 BSND CCDC57 CEP170B CKS1B CMTM5 CMTM6 CPD DGAT2L6 DNAJB9 DST FBXO2 GAREM2 GOLGB1 HNRNPM HSD17B13 HSPB1 MAL2 MKI67 MYH10 PCM1 PCYT1B PSMC3 RAB11FIP4 RNF168 SF3B2 SPECC1L SYNE1 TNFRSF10D UBE2G2 UBE2Q1 UIMC1 VPS11 ZNF483	14 interacting genes: CBX3 CBX5 CDK1 ECPAS HINFP KIF15 NIFK PRKCB PTEN SMN1 SUMO2 TK1 TRIM55 TRIM63
Entrez ID		23392	4288
HPRD ID		11078	08902
Ensembl ID		ENSG00000136813	ENSG00000148773
Uniprot IDs			P46013
PDB IDs			1R21 2AFF 5J28
Enriched GO Terms of Interacting Partners?
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