ENAH and KLHDC3

		ENAH	KLHDC3
Description		ENAH actin regulator	kelch domain containing 3
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Lamellipodium Cell Junction Filopodium Synapse	Chromatin Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Actin Binding Protein Binding Profilin Binding SH3 Domain Binding WW Domain Binding	Chromatin Binding Protein Binding
	Biological Process	Axon Guidance Actin Polymerization Or Depolymerization Actin Polymerization-dependent Cell Motility	Reciprocal Meiotic Recombination IRE1-mediated Unfolded Protein Response
Pathways		Generation of second messenger molecules Signaling by ROBO receptors Signaling by ROBO receptors	XBP1(S) activates chaperone genes
Drugs
Diseases
GWAS		Delirium ( 29631748) Depression in smokers ( 30219690) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Neuroticism ( 27067015) Obesity-related traits ( 23251661)
Interacting Genes		27 interacting genes: ABI1 ABI2 ABI3 ABL1 APBB1 BAIAP2 DNMBP EVL FAT1 FYB1 GPHN HMGB1 KLHDC3 MAPK1 PFN1 PRPF40A RAC1 RAD51 ROBO4 SPTA1 TERF2IP TES VASP WAS XIRP1 YAP1 ZYX	1 interacting genes: ENAH
Entrez ID		55740	116138
HPRD ID		12360	13922
Ensembl ID		ENSG00000154380	ENSG00000124702
Uniprot IDs		A0A4D6J698 Q8N8S7	Q9BQ90
PDB IDs		2HO2 2IYB 2XQN 4MY6 5N91 5N9C 5N9P 5NAJ 5NBF 5NBX 5NC2 5NC7 5NCF 5NCG 5NCP 5ND0 5NDU 5NEG 6RCF 6RCJ 6RD2 6XVT 6XXR 7A5M
Enriched GO Terms of Interacting Partners?
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