AP1G1 and ARFRP1

Data Source:
BioGRID (pull down)

		AP1G1	ARFRP1
Description		adaptor related protein complex 1 subunit gamma 1	ADP ribosylation factor related protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Lysosomal Membrane Golgi Apparatus Cytosol Membrane AP-1 Adaptor Complex Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle Recycling Endosome	Golgi Apparatus Trans-Golgi Network Cytosol Membrane Trans-Golgi Network Membrane
	Molecular Function	Protein Binding Kinesin Binding GTP-dependent Protein Binding Small GTPase Binding Clathrin Adaptor Activity Cargo Adaptor Activity	GTPase Activity Protein Binding GTP Binding
	Biological Process	Intracellular Protein Transport Golgi To Vacuole Transport Receptor-mediated Endocytosis Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Melanosome Organization Endosome To Melanosome Transport Positive Regulation Of Natural Killer Cell Degranulation Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Defense Response To Virus By Virus Golgi To Lysosome Transport	Intracellular Protein Transport Signal Transduction Gastrulation Protein Localization To Organelle Protein Localization To Golgi Apparatus Retrograde Transport, Endosome To Golgi Golgi To Plasma Membrane Protein Transport
Pathways		Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis	Retrograde transport at the Trans-Golgi-Network Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		General cognitive ability ( 29844566) HDL cholesterol levels ( 32203549) Post bronchodilator FEV1 ( 26634245) Refractive error ( 32231278) Superior temporal sulcus banks volume ( 31530798)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Crohn's disease ( 28067908) Estimated glomerular filtration rate ( 30604766) Inflammatory bowel disease ( 28067908) Platelet count ( 32888494) Prostate cancer ( 23535732) Refractive error ( 32231278) Ulcerative colitis ( 28067908)
Interacting Genes		27 interacting genes: AAGAB AFTPH AP1AR AP1B1 AP1M2 AP1S1 AP1S2 ARF1 ARFRP1 BAALC CCDC91 CLINT1 CLTC DNER EPS15 HEATR5B KIF13A MAP1A PSEN2 RABEP1 RABGEF1 SNX9 SPTB SYNRG SYP UBL7 ZNF512B	6 interacting genes: AP1G1 AP1M1 CYTH1 GLP1R SMAD4 VANGL2
Entrez ID		164	10139
HPRD ID		04637	05264
Ensembl ID		ENSG00000166747	ENSG00000101246
Uniprot IDs		A0A140VJE7 O43747 Q8IY97	A0A384P5U7 B7ZKY8 Q13795
PDB IDs		1IU1
Enriched GO Terms of Interacting Partners?
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