AP1G1 and AFTPH

Data Source:
HPRD (two hybrid)

		AP1G1	AFTPH
Description		adaptor related protein complex 1 subunit gamma 1	aftiphilin
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Lysosomal Membrane Golgi Apparatus Cytosol Membrane AP-1 Adaptor Complex Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle Recycling Endosome	Nucleoplasm Golgi Apparatus Cytosol AP-1 Adaptor Complex Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Kinesin Binding GTP-dependent Protein Binding Small GTPase Binding Clathrin Adaptor Activity Cargo Adaptor Activity	Clathrin Binding
	Biological Process	Intracellular Protein Transport Golgi To Vacuole Transport Receptor-mediated Endocytosis Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Melanosome Organization Endosome To Melanosome Transport Positive Regulation Of Natural Killer Cell Degranulation Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Defense Response To Virus By Virus Golgi To Lysosome Transport	Protein Transport Intracellular Transport
Pathways		Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		General cognitive ability ( 29844566) HDL cholesterol levels ( 32203549) Post bronchodilator FEV1 ( 26634245) Refractive error ( 32231278) Superior temporal sulcus banks volume ( 31530798)	Delirium ( 29631748) Lung adenocarcinoma ( 31326317) Metabolite levels ( 23823483)
Interacting Genes		27 interacting genes: AAGAB AFTPH AP1AR AP1B1 AP1M2 AP1S1 AP1S2 ARF1 ARFRP1 BAALC CCDC91 CLINT1 CLTC DNER EPS15 HEATR5B KIF13A MAP1A PSEN2 RABEP1 RABGEF1 SNX9 SPTB SYNRG SYP UBL7 ZNF512B	9 interacting genes: AP1G1 AP1G2 CLTC GGA1 GGA2 GGA3 LIG4 STAT5B UBE3A
Entrez ID		164	54812
HPRD ID		04637	10635
Ensembl ID		ENSG00000166747	ENSG00000119844
Uniprot IDs		A0A140VJE7 O43747 Q8IY97	Q53GW0 Q6ULP2
PDB IDs		1IU1
Enriched GO Terms of Interacting Partners?
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