AP1G1 and DNER

Data Source:
HPRD (in vivo)

		AP1G1	DNER
Description		adaptor related protein complex 1 subunit gamma 1	delta/notch like EGF repeat containing
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Lysosomal Membrane Golgi Apparatus Cytosol Membrane AP-1 Adaptor Complex Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle Recycling Endosome	Early Endosome Plasma Membrane Integral Component Of Membrane Dendrite Neuronal Cell Body
	Molecular Function	Protein Binding Kinesin Binding GTP-dependent Protein Binding Small GTPase Binding Clathrin Adaptor Activity Cargo Adaptor Activity	Transmembrane Signaling Receptor Activity Notch Binding Calcium Ion Binding Protein Binding Clathrin Binding
	Biological Process	Intracellular Protein Transport Golgi To Vacuole Transport Receptor-mediated Endocytosis Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Melanosome Organization Endosome To Melanosome Transport Positive Regulation Of Natural Killer Cell Degranulation Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Defense Response To Virus By Virus Golgi To Lysosome Transport	Neuron Migration Endocytosis Notch Signaling Pathway Notch Receptor Processing Synapse Assembly Central Nervous System Development Glial Cell Differentiation Skeletal Muscle Fiber Development
Pathways		Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis	Activated NOTCH1 Transmits Signal to the Nucleus
Drugs
Diseases
GWAS		General cognitive ability ( 29844566) HDL cholesterol levels ( 32203549) Post bronchodilator FEV1 ( 26634245) Refractive error ( 32231278) Superior temporal sulcus banks volume ( 31530798)	Blood protein levels ( 30072576) Carotid intima media thickness x smoking interaction ( 32117412) Hand grip strength ( 29691431) Metabolite levels ( 23823483) Pulmonary function (smoking interaction) ( 23284291) Type 2 diabetes ( 24101674)
Interacting Genes		27 interacting genes: AAGAB AFTPH AP1AR AP1B1 AP1M2 AP1S1 AP1S2 ARF1 ARFRP1 BAALC CCDC91 CLINT1 CLTC DNER EPS15 HEATR5B KIF13A MAP1A PSEN2 RABEP1 RABGEF1 SNX9 SPTB SYNRG SYP UBL7 ZNF512B	2 interacting genes: AP1G1 PDLIM7
Entrez ID		164	92737
HPRD ID		04637	09531
Ensembl ID		ENSG00000166747	ENSG00000187957
Uniprot IDs		A0A140VJE7 O43747 Q8IY97	Q8NFT8
PDB IDs		1IU1
Enriched GO Terms of Interacting Partners?
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