ARFRP1 and VANGL2

Data Source:
BioGRID (pull down)

		ARFRP1	VANGL2
Description		ADP ribosylation factor related protein 1	VANGL planar cell polarity protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Trans-Golgi Network Cytosol Membrane Trans-Golgi Network Membrane	Plasma Membrane Cell-cell Junction Integral Component Of Membrane Apical Plasma Membrane Lateral Plasma Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding	Protein Binding
	Biological Process	Intracellular Protein Transport Signal Transduction Gastrulation Protein Localization To Organelle Protein Localization To Golgi Apparatus Retrograde Transport, Endosome To Golgi Golgi To Plasma Membrane Protein Transport	Establishment Of Planar Polarity Neural Tube Closure Heart Looping Cell Migration Involved In Kidney Development Apical Protein Localization Wnt Signaling Pathway, Planar Cell Polarity Pathway Non-motile Cilium Assembly
Pathways		Retrograde transport at the Trans-Golgi-Network Retrograde transport at the Trans-Golgi-Network	PCP/CE pathway Asymmetric localization of PCP proteins
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Crohn's disease ( 28067908) Estimated glomerular filtration rate ( 30604766) Inflammatory bowel disease ( 28067908) Platelet count ( 32888494) Prostate cancer ( 23535732) Refractive error ( 32231278) Ulcerative colitis ( 28067908)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cognitive performance ( 19734545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Left-handedness ( 32989287) Multiple sclerosis ( 31604244 24076602) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Systemic lupus erythematosus ( 28714469)
Interacting Genes		6 interacting genes: AP1G1 AP1M1 CYTH1 GLP1R SMAD4 VANGL2	5 interacting genes: AP1M1 ARFRP1 DVL1 MAGI3 SQSTM1
Entrez ID		10139	57216
HPRD ID		05264	02758
Ensembl ID		ENSG00000101246	ENSG00000162738
Uniprot IDs		A0A384P5U7 B7ZKY8 Q13795	A8K4L6 Q9ULK5
PDB IDs
Enriched GO Terms of Interacting Partners?
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