PRR22 and PPIL1

Data Source:
BioGRID (two hybrid)

		PRR22	PPIL1
Description		proline rich 22	peptidylprolyl isomerase like 1
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function		Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Cyclosporin A Binding Disordered Domain Specific Binding
	Biological Process		MRNA Splicing, Via Spliceosome Protein Peptidyl-prolyl Isomerization Protein Folding
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Acne (severe) ( 24927181) Blood protein levels ( 30072576 29875488) Heart rate ( 28610988) Heart rate response to exercise ( 29769521) Heart rate response to recovery post exercise ( 29769521) Heart rate variability traits (pvRSA/HF) ( 28613276) Heart rate variability traits (RMSSD) ( 28613276) Heart rate variability traits (SDNN) ( 28613276) Resting heart rate ( 27798624) Weight ( 28552196)
Interacting Genes		26 interacting genes: CDC23 COX5B CREB5 CRYBA2 CRYBA4 CYSRT1 DOK6 FOXH1 GPS2 GRB2 HGS HNRNPF KCTD7 KRTAP26-1 MKRN3 NELFA OTX1 PATZ1 PPIL1 SMYD1 SNRPB TFAP2D TNS2 TRAPPC6A UFSP1 VGLL3	24 interacting genes: COL17A1 CPSF6 DDIT4L GADD45G HNRNPA1 HNRNPUL1 KPRP LHX2 LNX2 N4BP2L2 POU6F2 PPP1R8 PRR22 PRR35 RBM42 RIMBP3 SF3B3 SNW1 SPDYE4 SRPK1 SRPK2 TCF4 THOC5 WDR77
Entrez ID		163154	51645
HPRD ID		14501	03194
Ensembl ID		ENSG00000212123	ENSG00000137168
Uniprot IDs		Q8IZ63	A0A024RCX8 Q9Y3C6
PDB IDs			1XWN 2K7N 2X7K 5MQF 5XJC 5YZG 5Z56 5Z57 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV 6ZYM
Enriched GO Terms of Interacting Partners?
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