RIBC1 and ATP6V0D2

Data Source:
BioGRID (two hybrid)

		RIBC1	ATP6V0D2
Description		RIB43A domain with coiled-coils 1	ATPase H+ transporting V0 subunit d2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Lysosomal Membrane Early Endosome Endosome Membrane Membrane Apical Plasma Membrane Vacuolar Proton-transporting V-type ATPase Complex Phagocytic Vesicle Membrane Proton-transporting V-type ATPase, V0 Domain Plasma Membrane Proton-transporting V-type ATPase Complex Extracellular Exosome
	Molecular Function	Protein Binding	Protein Binding Proton-transporting ATPase Activity, Rotational Mechanism
	Biological Process		Vacuolar Transport Vacuolar Acidification Insulin Receptor Signaling Pathway Regulation Of Macroautophagy Transferrin Transport Ion Transmembrane Transport Phagosome Acidification Proton Transmembrane Transport
Pathways			ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs			Tiludronic acid
Diseases
GWAS		Bipolar disorder ( 31043756)	Adverse response to lamotrigine and phenytoin ( 22379998) Neutrophil count ( 32888494)
Interacting Genes		25 interacting genes: ATP6V0D2 BORCS6 CCNC EMILIN1 GOLGA2 GPSM1 HSF2BP KRT15 KRT31 KRT36 LDOC1 MISP MKRN3 MPPED2 OIP5 PFDN5 RINT1 TBC1D21 TEX11 TLE5 TOX2 TRIM23 TRIM27 USHBP1 VPS37C	20 interacting genes: ADRM1 AGO3 ARID5A CENPP CRX IKZF3 INCA1 MEOX2 NDUFB8 NICN1 PAX6 PHF12 POMC RBM15B REL RIBC1 RPS3 RUSC1 SEPTIN2 ZNF474
Entrez ID		158787	245972
HPRD ID		06553	16522
Ensembl ID		ENSG00000158423	ENSG00000147614
Uniprot IDs		A0A024R9X7 Q8N443	A0A024R991 Q8N8Y2
PDB IDs
Enriched GO Terms of Interacting Partners?
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