WDR77 and RIOK1

Data Source:
BioGRID (pull down)

		WDR77	RIOK1
Description		WD repeat domain 77	RIO kinase 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Methylosome Pole Plasm	Nucleoplasm Cytosol Preribosome, Small Subunit Precursor Methyltransferase Complex
	Molecular Function	Protein Binding Methyl-CpG Binding Nuclear Receptor Coactivator Activity	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Hydrolase Activity Metal Ion Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Spliceosomal SnRNP Assembly Regulation Of Transcription By RNA Polymerase II Pole Plasm Assembly Positive Regulation Of Cell Population Proliferation Positive Regulation Of Transcription, DNA-templated Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development	Protein Phosphorylation Maturation Of SSU-rRNA Ribosomal Small Subunit Biogenesis Positive Regulation Of RRNA Processing
Pathways		snRNP Assembly RMTs methylate histone arginines	Major pathway of rRNA processing in the nucleolus and cytosol
Drugs			Fostamatinib
Diseases
GWAS			Response to fenofibrate (triglyceride levels) ( 27002377)
Interacting Genes		44 interacting genes: AQR BAG2 CDK19 CDK8 CLNS1A CREBBP CTDP1 GLI1 GPKOW H2AC21 HNRNPM LSM3 NKX3-1 PCBP2 PPIL1 PPP1R8 PQBP1 PRKG1 PRKG2 PRMT5 QKI RBM5 RIOK1 SAP30BP SF1 SF3A1 SF3B4 SIRT7 SMAD1 SMYD1 SNRPB SNRPC SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SUZ12 THOC1 TOE1 YWHAB YWHAQ ZMYND19 ZNF207	7 interacting genes: APP CSNK2A1 FBXO6 KDM1A SETD7 WDR77 YWHAB
Entrez ID		79084	83732
HPRD ID		14387	17978
Ensembl ID		ENSG00000116455	ENSG00000124784
Uniprot IDs		A0A024R0H7 Q9BQA1	Q9BRS2
PDB IDs		4GQB 4X60 4X61 4X63 5C9Z 5EMJ 5EMK 5EML 5EMM 5FA5 6CKC 6K1S 6RLL 6RLQ 6UXX 6UXY 6V0N 6V0O	4OTP 6G5I 6V0N
Enriched GO Terms of Interacting Partners?
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