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TEKT4 and GATA1
Data Source:
BioGRID
(two hybrid)
TEKT4
GATA1
Description
tektin 4
GATA binding protein 1
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Microtubule Cytoskeleton
Sperm Flagellum
Chromatin
Nucleus
Nucleoplasm
Transcription Regulator Complex
Transcription Repressor Complex
Protein-DNA Complex
Molecular Function
Protein Binding
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
RNA Polymerase II Transcription Factor Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
P53 Binding
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Zinc Ion Binding
Chromatin DNA Binding
Sequence-specific DNA Binding
C2H2 Zinc Finger Domain Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Cilium Assembly
Cilium Movement Involved In Cell Motility
Negative Regulation Of Transcription By RNA Polymerase II
In Utero Embryonic Development
Regulation Of Transcription By RNA Polymerase II
Cell-cell Signaling
Blood Coagulation
Negative Regulation Of Cell Population Proliferation
Male Gonad Development
Regulation Of Glycoprotein Biosynthetic Process
Regulation Of Definitive Erythrocyte Differentiation
Regulation Of Primitive Erythrocyte Differentiation
Erythrocyte Differentiation
Megakaryocyte Differentiation
Platelet Formation
Basophil Differentiation
Eosinophil Differentiation
Negative Regulation Of Bone Mineralization
Positive Regulation Of Osteoblast Proliferation
Embryonic Hemopoiesis
Eosinophil Fate Commitment
Negative Regulation Of Apoptotic Process
Cell Fate Commitment
Positive Regulation Of Erythrocyte Differentiation
Regulation Of Megakaryocyte Differentiation
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Erythrocyte Development
Homeostasis Of Number Of Cells Within A Tissue
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Platelet Aggregation
Transcriptional Activation By Promoter-enhancer Looping
Dendritic Cell Differentiation
Cellular Response To Thyroid Hormone Stimulus
Regulation Of Hematopoietic Stem Cell Differentiation
Negative Regulation Of Transcription Regulatory Region DNA Binding
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
RUNX1 regulates transcription of genes involved in differentiation of HSCs
Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
Thrombocytopenia (THC); Familial platelet disorder with associated myeloid malignancy (FPDMM)
Congenital dyserythropoietic anemias (CDAs)
GWAS
Eosinophil counts (
32888494
)
Eosinophil percentage of white cells (
32888494
)
Interacting Genes
104 interacting genes:
ACBD4
AKAP8L
ALAS1
AMMECR1
ANKRD55
ARID5A
ATG5
BCL6
BLZF1
BORCS8-MEF2B
C11orf1
C1orf109
C9orf24
CTDSP1
DDIT4L
EFHC2
EYA2
FAM220A
GATA1
GPSM1
GRB10
GSE1
HCK
HNRNPH1
HNRNPM
HOXA1
HOXB5
HOXC8
IKZF3
INCA1
KPRP
KRT15
KRT18
KRT34
KRT35
KRT75
KRT86
KRTAP11-1
KRTAP13-1
KRTAP13-3
KRTAP19-1
KRTAP19-2
KRTAP19-6
KRTAP26-1
KRTAP6-2
KRTAP6-3
KRTAP7-1
LASP1
LMCD1
LNX1
MAGEA4
MIIP
MORN3
MYOZ3
NANOS3
NFKBID
NR5A1
PCSK5
PHF11
PKP2
PLAGL2
POLDIP3
PPP1R13B
PPP1R32
PRDM14
PRDM6
PROP1
PSMA1
PTH1R
RAMAC
RARA
RBM48
RECK
RFX6
RUSC1
SCN5A
SLC25A6
SMAD3
SOCS4
SPATA8
SPATC1L
SPG21
SUV39H1
TADA2A
TEKT1
TFAP4
TOX2
TRIB3
TRIP6
TSPAN4
UBASH3A
USP2
VGLL1
ZFP90
ZIM2
ZMYND12
ZNF20
ZNF417
ZNF426
ZNF474
ZNF552
ZNF581
ZNF655
ZNF688
85 interacting genes:
AKT1
ARID1A
ARMC7
ATP6V0D1
BCL6
CASP3
CCDC24
CEBPE
CHRD
CREBBP
DGCR6L
DNMT3L
FANCG
FANCL
FBF1
FHL3
FLI1
FRS3
GLRX3
GOLGA2
GRAP2
HDAC3
HDAC4
HDAC5
HEMGN
HEXIM2
HEY1
HOXA1
HSPA4
KANK2
KRTAP10-5
KRTAP3-2
KRTAP4-11
KRTAP4-5
KRTAP9-2
LMO2
LZTS2
MAPK1
MAPK3
MAPK6
MDFI
MED1
MGAT5B
MKRN3
PITX1
PLSCR4
PML
PNMA1
PPP1R16B
PRKAA1
PRKAB2
PSMF1
RADIL
RAI1
RBPMS
RIN3
SMARCA4
SMARCB1
SMARCC1
SMARCC2
SMARCD1
SMARCE1
SP1
SPI1
SPIB
SRA1
STAT3
TAF7
TAL1
TAX1BP3
TEKT4
TLE5
TNS2
TRAF1
TRIM25
TRIM29
TRIP6
USP7
ZBTB16
ZBTB22
ZDHHC17
ZFPM1
ZFPM2
ZNF521
ZZZ3
Entrez ID
150483
2623
HPRD ID
14518
02372
Ensembl ID
ENSG00000163060
ENSG00000102145
Uniprot IDs
A0A384MEB7
Q8WW24
P15976
PDB IDs
6G0Q
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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