CTNND1 and PLPP3

Data Source:
BioGRID (pull down)

		CTNND1	PLPP3
Description		catenin delta 1	phospholipid phosphatase 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Cell-cell Junction Adherens Junction Zonula Adherens Catenin Complex Lamellipodium Growth Cone Midbody Dendritic Spine Extracellular Exosome Schaffer Collateral - CA1 Synapse Hippocampal Mossy Fiber To CA3 Synapse Presynaptic Active Zone Cytoplasmic Component Glutamatergic Synapse Postsynaptic Density, Intracellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Trans-Golgi Network Plasma Membrane Integral Component Of Plasma Membrane Adherens Junction Membrane Integral Component Of Membrane Basolateral Plasma Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Membrane Raft Endoplasmic Reticulum Exit Site
	Molecular Function	Signaling Receptor Binding Protein Binding Protein Kinase Binding Cadherin Binding	Integrin Binding Protein Binding Phosphatidate Phosphatase Activity Sphingosine-1-phosphate Phosphatase Activity Lipid Phosphatase Activity Ceramide-1-phosphate Phosphatase Activity
	Biological Process	Cell-cell Junction Assembly Brain Development Wnt Signaling Pathway Adherens Junction Organization Entry Of Bacterium Into Host Cell Cell-cell Adhesion Mediated By Cadherin Protein Stabilization Negative Regulation Of Canonical Wnt Signaling Pathway Cell-cell Adhesion Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels	Negative Regulation Of Protein Phosphorylation Phospholipid Metabolic Process Sphingosine Metabolic Process Ceramide Metabolic Process Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Signal Transduction Integrin-mediated Signaling Pathway Regulation Of Wnt Signaling Pathway Sphingolipid Biosynthetic Process Cell-cell Adhesion Mediated By Integrin Homotypic Cell-cell Adhesion Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Endothelial Cell Migration Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Cell-cell Adhesion Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Wound Healing Phospholipid Dephosphorylation Protein Stabilization Positive Regulation Of DNA-binding Transcription Factor Activity Canonical Wnt Signaling Pathway
Pathways		Adherens junctions interactions VEGFR2 mediated vascular permeability InlA-mediated entry of Listeria monocytogenes into host cells	Sphingolipid de novo biosynthesis
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) High light scatter reticulocyte percentage of red cells ( 32888494) Household income (MTAG) ( 31844048) Neuroticism ( 29255261) Parkinson's disease ( 27182965) Pulse pressure ( 27841878 30578418) Reticulocyte fraction of red cells ( 32888494) Schizophrenia ( 25056061 29483656) Systolic blood pressure ( 27841878)	Coronary artery disease ( 30104761 33020668) Heel bone mineral density ( 30598549) Low density lipoprotein cholesterol levels ( 29403010)
Interacting Genes		32 interacting genes: ACTA1 APP CDH1 CDH24 CDH3 CDH5 COL17A1 CTTN EGFR ERBIN FER GRIK2 GSK3B JUP KCTD6 LCK MAPK1 MAPK3 MTNR1B MUC1 PLPP3 PSEN1 PTPN6 PTPRJ PTPRM RPS6KA3 SMURF1 SNCA SRC SUMO2 YWHAG ZBTB33	4 interacting genes: APP BCAR1 CTNND1 SHC1
Entrez ID		1500	8613
HPRD ID		03026	06179
Ensembl ID		ENSG00000198561	ENSG00000162407
Uniprot IDs		O60716	O14495
PDB IDs		3L6X 3L6Y
Enriched GO Terms of Interacting Partners?
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