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PLPP3
Description
phospholipid phosphatase 3
Image
No pdb structure
GO Annotations
Cellular Component
Golgi Membrane
Endoplasmic Reticulum Membrane
Golgi Apparatus
Trans-Golgi Network
Plasma Membrane
Integral Component Of Plasma Membrane
Adherens Junction
Membrane
Integral Component Of Membrane
Basolateral Plasma Membrane
Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
Membrane Raft
Endoplasmic Reticulum Exit Site
Molecular Function
Integrin Binding
Protein Binding
Phosphatidate Phosphatase Activity
Sphingosine-1-phosphate Phosphatase Activity
Lipid Phosphatase Activity
Ceramide-1-phosphate Phosphatase Activity
Biological Process
Negative Regulation Of Protein Phosphorylation
Phospholipid Metabolic Process
Sphingosine Metabolic Process
Ceramide Metabolic Process
Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum
Signal Transduction
Integrin-mediated Signaling Pathway
Regulation Of Wnt Signaling Pathway
Sphingolipid Biosynthetic Process
Cell-cell Adhesion Mediated By Integrin
Homotypic Cell-cell Adhesion
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Endothelial Cell Migration
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Cell-cell Adhesion
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Wound Healing
Phospholipid Dephosphorylation
Protein Stabilization
Positive Regulation Of DNA-binding Transcription Factor Activity
Canonical Wnt Signaling Pathway
Pathways
Sphingolipid de novo biosynthesis
Drugs
Diseases
GWAS
Coronary artery disease (
30104761
33020668
)
Heel bone mineral density (
30598549
)
Low density lipoprotein cholesterol levels (
29403010
)
Interacting Genes
4 interacting genes:
APP
BCAR1
CTNND1
SHC1
Entrez ID
8613
HPRD ID
06179
Ensembl ID
ENSG00000162407
Uniprot IDs
O14495
PDB IDs
Enriched GO Terms of Interacting Partners
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