CTNND1 and CDH3

Data Source:
HPRD (in vivo)

		CTNND1	CDH3
Description		catenin delta 1	cadherin 3
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Cell-cell Junction Adherens Junction Zonula Adherens Catenin Complex Lamellipodium Growth Cone Midbody Dendritic Spine Extracellular Exosome Schaffer Collateral - CA1 Synapse Hippocampal Mossy Fiber To CA3 Synapse Presynaptic Active Zone Cytoplasmic Component Glutamatergic Synapse Postsynaptic Density, Intracellular Component	Cytoplasm Plasma Membrane Adherens Junction Integral Component Of Membrane Catenin Complex Cell Junction
	Molecular Function	Signaling Receptor Binding Protein Binding Protein Kinase Binding Cadherin Binding	Molecular_function Calcium Ion Binding Cadherin Binding
	Biological Process	Cell-cell Junction Assembly Brain Development Wnt Signaling Pathway Adherens Junction Organization Entry Of Bacterium Into Host Cell Cell-cell Adhesion Mediated By Cadherin Protein Stabilization Negative Regulation Of Canonical Wnt Signaling Pathway Cell-cell Adhesion Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels	Retina Homeostasis Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Visual Perception Positive Regulation Of Gene Expression Positive Regulation Of Keratinocyte Proliferation Hair Cycle Process Keratinization Positive Regulation Of Monophenol Monooxygenase Activity Negative Regulation Of Transforming Growth Factor Beta2 Production Adherens Junction Organization Wound Healing Response To Drug Positive Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Positive Regulation Of Melanin Biosynthetic Process Negative Regulation Of Timing Of Catagen Regulation Of Hair Cycle By Canonical Wnt Signaling Pathway Positive Regulation Of Canonical Wnt Signaling Pathway Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Positive Regulation Of Melanosome Transport
Pathways		Adherens junctions interactions VEGFR2 mediated vascular permeability InlA-mediated entry of Listeria monocytogenes into host cells	Adherens junctions interactions
Drugs
Diseases			Hypotrichosis, congenital, with juvenile macular dystrophy Ectodermal dysplasia, ectrodactyly, and macular dystrophy (EEM syndrome)
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) High light scatter reticulocyte percentage of red cells ( 32888494) Household income (MTAG) ( 31844048) Neuroticism ( 29255261) Parkinson's disease ( 27182965) Pulse pressure ( 27841878 30578418) Reticulocyte fraction of red cells ( 32888494) Schizophrenia ( 25056061 29483656) Systolic blood pressure ( 27841878)	Cutaneous melanoma or hair colour ( 32341527) Glycated hemoglobin levels ( 28898252) Mean reticulocyte volume ( 32888494) Multiple sclerosis ( 31604244 24076602) Platelet count ( 32888494) Red cell distribution width ( 27863252) Ulcerative colitis ( 28067908)
Interacting Genes		32 interacting genes: ACTA1 APP CDH1 CDH24 CDH3 CDH5 COL17A1 CTTN EGFR ERBIN FER GRIK2 GSK3B JUP KCTD6 LCK MAPK1 MAPK3 MTNR1B MUC1 PLPP3 PSEN1 PTPN6 PTPRJ PTPRM RPS6KA3 SMURF1 SNCA SRC SUMO2 YWHAG ZBTB33	3 interacting genes: CTNNA1 CTNNB1 CTNND1
Entrez ID		1500	1001
HPRD ID		03026	00227
Ensembl ID		ENSG00000198561	ENSG00000062038
Uniprot IDs		O60716	B4DLF0 P22223
PDB IDs		3L6X 3L6Y	4OY9 4ZML 4ZMN 4ZMO 4ZMP 4ZMQ 4ZMT 4ZMV 4ZMW 4ZMX 4ZMY 4ZMZ 5JYL 5JYM
Enriched GO Terms of Interacting Partners?
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