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CTF1 and LIFR
Data Source:
HPRD
(in vivo)
CTF1
LIFR
Description
cardiotrophin 1
LIF receptor subunit alpha
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Plasma Membrane
Integral Component Of Plasma Membrane
External Side Of Plasma Membrane
Receptor Complex
Extracellular Exosome
Molecular Function
Cytokine Activity
Leukemia Inhibitory Factor Receptor Binding
Protein Binding
Cytokine Receptor Activity
Ciliary Neurotrophic Factor Receptor Activity
Leukemia Inhibitory Factor Receptor Activity
Oncostatin-M Receptor Activity
Ciliary Neurotrophic Factor Receptor Binding
Protein Binding
Growth Factor Binding
Cytokine Binding
Biological Process
Cell Surface Receptor Signaling Pathway
Cell-cell Signaling
Muscle Organ Development
Positive Regulation Of Cell Population Proliferation
Cytokine-mediated Signaling Pathway
Neuron Differentiation
Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein
Neuron Development
Leukemia Inhibitory Factor Signaling Pathway
Regulation Of Cytokine-mediated Signaling Pathway
Cell Surface Receptor Signaling Pathway
Positive Regulation Of Cell Population Proliferation
Cytokine-mediated Signaling Pathway
Response To Cytokine
Oncostatin-M-mediated Signaling Pathway
Leukemia Inhibitory Factor Signaling Pathway
Ciliary Neurotrophic Factor-mediated Signaling Pathway
Pathways
IL-6-type cytokine receptor ligand interactions
IL-6-type cytokine receptor ligand interactions
RUNX1 regulates transcription of genes involved in interleukin signaling
Drugs
Diseases
Stuve-Wiedemann syndrome
GWAS
Red blood cell count (
27863252
)
Triglyceride levels (
28334899
)
Triglycerides (
24097068
20686565
)
Blood protein levels (
30072576
)
Crohn's disease (
26192919
)
Inflammatory bowel disease (
26192919
)
Pursuit maintenance gain (
29064472
)
Ulcerative colitis (
26192919
)
Interacting Genes
5 interacting genes:
APP
EP300
IL6ST
LIFR
MAGEA6
12 interacting genes:
CNTF
CNTFR
CTF1
IL31RA
IL6ST
LIF
MAPK1
OSM
PLCG1
POU2F1
PTPN11
PTPN6
Entrez ID
1489
3977
HPRD ID
02699
01048
Ensembl ID
ENSG00000150281
ENSG00000113594
Uniprot IDs
Q16619
A8K1Z4
P42702
PDB IDs
3E0G
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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