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CTAG1B and HCK
Data Source:
BioGRID
(two hybrid)
CTAG1B
HCK
Description
cancer/testis antigen 1B
HCK proto-oncogene, Src family tyrosine kinase
Image
GO Annotations
Cellular Component
Cytoplasm
Nucleus
Lysosome
Golgi Apparatus
Cytosol
Actin Filament
Plasma Membrane
Caveola
Focal Adhesion
Transport Vesicle
Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
Cell Projection
Intracellular Membrane-bounded Organelle
Molecular Function
Protein Binding
Identical Protein Binding
Phosphotyrosine Residue Binding
Protein Tyrosine Kinase Activity
Non-membrane Spanning Protein Tyrosine Kinase Activity
Signaling Receptor Binding
Protein Binding
ATP Binding
Biological Process
Positive Regulation Of Transcription By RNA Polymerase II
TRNA Threonylcarbamoyladenosine Metabolic Process
Leukocyte Migration Involved In Immune Response
Innate Immune Response-activating Signal Transduction
Protein Phosphorylation
Inflammatory Response
Cell Adhesion
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Integrin-mediated Signaling Pathway
Mesoderm Development
Positive Regulation Of Cell Population Proliferation
Regulation Of Cell Shape
Peptidyl-tyrosine Phosphorylation
Cytokine-mediated Signaling Pathway
Cell Differentiation
Positive Regulation Of Actin Filament Polymerization
Lipopolysaccharide-mediated Signaling Pathway
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Negative Regulation Of Apoptotic Process
Leukocyte Degranulation
Innate Immune Response
Respiratory Burst After Phagocytosis
Protein Autophosphorylation
Regulation Of Defense Response To Virus By Virus
Regulation Of Inflammatory Response
Regulation Of Phagocytosis
Regulation Of DNA-binding Transcription Factor Activity
Interferon-gamma-mediated Signaling Pathway
Regulation Of Podosome Assembly
Positive Regulation Of Actin Cytoskeleton Reorganization
Pathways
Nef and signal transduction
FCGR activation
Regulation of signaling by CBL
Regulation of signaling by CBL
FCGR3A-mediated IL10 synthesis
FCGR3A-mediated phagocytosis
FLT3 signaling through SRC family kinases
Drugs
1-Ter-Butyl-3-P-Tolyl-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine
Phosphonotyrosine
Quercetin
Bosutinib
Fostamatinib
Diseases
GWAS
Adult body size (
32376654
)
Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) (
30940143
)
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Inflammatory bowel disease (
23128233
)
Migraine (
27322543
)
Interacting Genes
81 interacting genes:
ACTN3
ALOX15B
ARHGEF28
ATP1A4
BAG6
BEX1
BEX2
BMF
BORCS8
BORCS8-MEF2B
C14orf119
C1orf109
CAMSAP1
CCDC116
CCHCR1
CDC37
CDKN2AIPNL
CHCHD2
CSTF2T
CTAG1A
CYTH4
DESI1
FCHSD2
FSD2
GATC
GNG13
GPSM3
GTF2I
GUCD1
HCK
HEMK1
HLA-DRB1
HLA-DRB3
HLA-DRB4
HLA-DRB5
KIF26A
KLHL38
LAMTOR1
LNPEP
LONRF3
MAGEC1
MEIS2
MGAT5B
MSGN1
NAB2
NCS1
NTAQ1
P4HA3
PEF1
PIH1D2
POLM
PSMB1
RANBP10
REX1BD
RSRC2
RTN4IP1
RUSC1
SEC14L4
SGTA
SGTB
SIKE1
SMG9
SOHLH1
SPAG8
STRA8
SUOX
TCEANC
TEPSIN
THOC1
TNPO2
TRIB3
TRIM55
TRIM63
TSGA10IP
UBE2V1
UBL5
UBQLN1
UBQLN2
USP20
VENTX
WWOX
116 interacting genes:
ABL1
ABL2
ACTB
ADAM15
AGK
AGR2
APP
AR
ARRB1
ASAP1
BCAR1
BCR
BPIFA1
BTK
CBL
CCDC88B
CCR3
CD2AP
CHST15
CREBBP
CSF2RB
CSF3R
CSK
CTAG1A
CTAG1B
CYB5D2
CYSRT1
DNM2
DOK1
DOK2
EGFR
ELMO1
ERBB2
ERBB3
ERBB4
EVL
FASLG
FCGR1A
FCGR2A
FHL2
FHL5
GAB1
GOPC
GRB14
HNRNPK
HSF2BP
IL6ST
INCA1
INPP5D
IRF2BPL
KHDRBS1
KIT
KPRP
KRT31
KRT34
KRT35
KRT36
KRT40
KRTAP1-1
KRTAP1-3
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP3-1
LCP2
LETMD1
LMNA
MAP4K5
MDK
MDM2
MET
MID2
MKRN3
MTUS2
NBPF19
NGEF
NOTCH2NLA
PAK2
PECAM1
PIK3CB
PIK3R1
PIK3R2
PLAUR
PLCG1
PLCG2
PLEKHG4
PNMA1
RAPGEF1
RASA1
RASA3
RBPMS
RPL10
SF3B3
SH2B2
SH3BP1
SH3KBP1
SKAP2
SOS1
SPRR2A
STAT3
TEKT4
TEPSIN
TNK2
TOX2
TP73
TRIM27
TRIP6
TRPV4
TSG101
UNC119
VAV1
WAS
WDCP
WIPF1
WNT2
ZSCAN4
Entrez ID
1485
3055
HPRD ID
02151
00796
Ensembl ID
ENSG00000184033
ENSG00000101336
Uniprot IDs
P78358
A8K4G3
P08631
PDB IDs
1S9W
2BNQ
2BNR
2F53
2F54
2P5E
2P5W
2PYE
3GJF
3HAE
3KLA
6AT5
6AVF
6AVG
6RP9
6RPA
6RPB
1AD5
1BU1
1QCF
2C0I
2C0O
2C0T
2HCK
2HK5
2OI3
2OJ2
3HCK
3NHN
3RBB
3REA
3REB
3VRY
3VRZ
3VS0
3VS1
3VS2
3VS3
3VS4
3VS5
3VS6
3VS7
4HCK
4LUD
4LUE
4ORZ
4U5W
5H09
5H0B
5H0E
5H0G
5H0H
5HCK
5NUH
5ZJ6
Enriched GO Terms of Interacting Partners
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