Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
CLDN5 and MPDZ
Data Source:
HPRD
(in vivo)
CLDN5
MPDZ
Description
claudin 5
multiple PDZ domain crumbs cell polarity complex component
Image
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Cell-cell Junction
Bicellular Tight Junction
Integral Component Of Membrane
Apicolateral Plasma Membrane
Cell Junction
Cortical Actin Cytoskeleton
Tight Junction
Cytoplasm
Bicellular Tight Junction
Postsynaptic Density
Apical Plasma Membrane
Apicolateral Plasma Membrane
Dendrite
Molecular Function
Structural Molecule Activity
Protein Binding
Identical Protein Binding
Protein Binding
Protein C-terminus Binding
Biological Process
Outflow Tract Morphogenesis
Cell-cell Junction Assembly
Cell Adhesion
Transforming Growth Factor Beta Receptor Signaling Pathway
Learning
Positive Regulation Of Cell Population Proliferation
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules
Negative Regulation Of Angiogenesis
Negative Regulation Of Cell Migration
Positive Regulation Of Protein Binding
Maintenance Of Blood-brain Barrier
Negative Regulation Of Vascular Permeability
Roof Of Mouth Development
Face Morphogenesis
Bicellular Tight Junction Assembly
Tight Junction Assembly
Positive Regulation Of Establishment Of Endothelial Barrier
Positive Regulation Of Bicellular Tight Junction Assembly
Establishment Of Blood-retinal Barrier
Regulation Of Bicellular Tight Junction Assembly
Viral Process
Pathways
Tight junction interactions
RUNX1 regulates expression of components of tight junctions
Drugs
Diseases
GWAS
Central corneal thickness (
32528159
29760442
)
Corneal hysteresis (
30894546
)
Corneal structure (
23291589
)
Heel bone mineral density (
30598549
28869591
)
Refractive astigmatism (
30306274
)
Triglyceride levels (
32203549
)
Interacting Genes
40 interacting genes:
AQP1
BTNL8
CCDC167
CLDN3
CLRN2
CNPY3
CORIN
CTRL
CXCL9
CYB561A3
EFNA5
EHHADH
ERG28
ERMP1
FXYD6-FXYD2
GYPA
LAT
LHFPL5
MIP
MPDZ
PLP2
PLPPR2
PMP22
RPRM
SFTPC
SGCG
SLC35B4
SMIM3
TECR
TF
TJP1
TMEM128
TMEM140
TMEM14C
TMEM182
TMEM190
TMEM222
TSPAN2
VAMP5
YIPF1
16 interacting genes:
ABCA1
CAMK2A
CLDN1
CLDN5
CRHR1
CSPG4
DRD3
F11R
HTR2C
KIT
MTNR1A
PLEKHA1
PLEKHA2
RNF5
SYNGAP1
TSC22D2
Entrez ID
7122
8777
HPRD ID
03654
09155
Ensembl ID
ENSG00000184113
ENSG00000107186
Uniprot IDs
D3DX19
O00501
O75970
PDB IDs
2FCF
2FNE
2IWN
2IWO
2IWP
2IWQ
2O2T
2OPG
2QG1
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?