CLDN5 and BTNL8

Data Source:
BioGRID (two hybrid)

		CLDN5	BTNL8
Description		claudin 5	butyrophilin like 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell-cell Junction Bicellular Tight Junction Integral Component Of Membrane Apicolateral Plasma Membrane Cell Junction Cortical Actin Cytoskeleton Tight Junction	Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Structural Molecule Activity Protein Binding Identical Protein Binding	Signaling Receptor Binding Protein Binding
	Biological Process	Outflow Tract Morphogenesis Cell-cell Junction Assembly Cell Adhesion Transforming Growth Factor Beta Receptor Signaling Pathway Learning Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Negative Regulation Of Angiogenesis Negative Regulation Of Cell Migration Positive Regulation Of Protein Binding Maintenance Of Blood-brain Barrier Negative Regulation Of Vascular Permeability Roof Of Mouth Development Face Morphogenesis Bicellular Tight Junction Assembly Tight Junction Assembly Positive Regulation Of Establishment Of Endothelial Barrier Positive Regulation Of Bicellular Tight Junction Assembly Establishment Of Blood-retinal Barrier Regulation Of Bicellular Tight Junction Assembly	Regulation Of Cytokine Production Adaptive Immune Response T Cell Receptor Signaling Pathway
Pathways		Tight junction interactions RUNX1 regulates expression of components of tight junctions	Butyrophilin (BTN) family interactions
Drugs
Diseases
GWAS			Blood protein levels ( 30072576)
Interacting Genes		40 interacting genes: AQP1 BTNL8 CCDC167 CLDN3 CLRN2 CNPY3 CORIN CTRL CXCL9 CYB561A3 EFNA5 EHHADH ERG28 ERMP1 FXYD6-FXYD2 GYPA LAT LHFPL5 MIP MPDZ PLP2 PLPPR2 PMP22 RPRM SFTPC SGCG SLC35B4 SMIM3 TECR TF TJP1 TMEM128 TMEM140 TMEM14C TMEM182 TMEM190 TMEM222 TSPAN2 VAMP5 YIPF1	5 interacting genes: CLDN5 HHLA2 IFNGR2 MILR1 TFF1
Entrez ID		7122	79908
HPRD ID		03654	12549
Ensembl ID		ENSG00000184113	ENSG00000113303
Uniprot IDs		D3DX19 O00501	Q6UX41
PDB IDs
Enriched GO Terms of Interacting Partners?
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