ZNF534 and C1QC

Data Source:
BioGRID (two hybrid)

		ZNF534	C1QC
Description		zinc finger protein 534	complement C1q C chain
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Extracellular Region Collagen Trimer Extracellular Space Synapse Collagen-containing Extracellular Matrix Blood Microparticle Postsynapse
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Immune Response Complement Activation Complement Activation, Classical Pathway Regulation Of Complement Activation Negative Regulation Of Granulocyte Differentiation Innate Immune Response Negative Regulation Of Macrophage Differentiation Synapse Pruning
Pathways			Initial triggering of complement Classical antibody-mediated complement activation Regulation of Complement cascade
Drugs			Cetuximab Etanercept Palivizumab Daclizumab Bevacizumab Zinc Copper Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases			Classic complement pathway component defects, including the following eight diseases: C1q alpha-chain deficiency; C1q beta-chain deficiency; C1q gamma-chain deficiency; C1r deficiency; C1s deficiency; C2 deficiency; C3 deficiency; C4 deficiency
GWAS			Blood protein levels ( 30072576 29875488)
Interacting Genes		3 interacting genes: AGAP1 C1QC WDR83OS	6 interacting genes: C1QA C1QB FKBP2 PTX3 UBQLN2 ZNF534
Entrez ID		147658	714
HPRD ID		15824	00395
Ensembl ID		ENSG00000198633	ENSG00000159189
Uniprot IDs		Q1T7F5 Q1T7F6 Q76KX8	A0A024RAA7 P02747
PDB IDs			1PK6 2JG8 2JG9 2WNU 2WNV 5HKJ 5HZF 6FCZ 6Z6V
Enriched GO Terms of Interacting Partners?
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