CSK and SIT1

  • Data Source:
  • HPRD (in vivo)

CSK

SIT1

Description C-terminal Src kinase signaling threshold regulating transmembrane adaptor 1
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blood pressure ( 21909110)
  • Blood protein levels ( 30072576)
  • Caffeine consumption ( 21490707)
  • Coffee consumption ( 31959922)
  • Diastolic blood pressure ( 26390057 19430479 19430483)
  • Diastolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Diastolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
  • Hypertension ( 31513605)
  • Lung cancer ( 28604730)
  • Lung cancer in ever smokers ( 28604730)
  • Mean arterial pressure ( 27618448)
  • Mean arterial pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
  • Medication use (agents acting on the renin-angiotensin system) ( 31015401)
  • Medication use (beta blocking agents) ( 31015401)
  • Medication use (diuretics) ( 31015401)
  • Offspring birth weight ( 31043758)
  • Serum albumin level ( 29403010)
  • Systemic lupus erythematosus ( 27399966 26502338 28714469)
  • Systemic lupus erythematosus and Systemic sclerosis ( 23740937)
  • Systemic sclerosis ( 31672989)
  • Systolic blood pressure ( 30578418)
  • Systolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Systolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
  • Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel) ( 23648065)
Interacting Genes 51 interacting genes: ADRB2 ARRB1 CAV1 CD247 CD3E CD44 CDC45 CDH5 CREBBP DAB2 DOK1 DOK2 DOK3 FGR FHL2 FYN G3BP1 GJA1 GSN HCK HNRNPK ID3 IGF1R INSR KANK4 KHDRBS1 LAIR1 LCK LYN MAPK15 PAG1 PDPK1 PECAM1 PLD2 PRKACA PTK2 PTPN12 PTPN18 PTPN22 PXN RASA1 RGS16 SDC3 SHC1 SIT1 SRC TGFB1I1 TLR3 UBE2I ZAP70 ZNF212 17 interacting genes: APOL2 BMP10 CLRN2 CSK FYN GRB2 ITM2A LCK MALL PLN PTPN11 SYK TMBIM6 TMEM140 TSPAN33 UPK1B ZAP70
Entrez ID 1445 27240
HPRD ID 00496 05394
Ensembl ID ENSG00000103653 ENSG00000137078
Uniprot IDs A8K3B6 B2R6Q4 P41240 Q9Y3P8
PDB IDs 1BYG 1CSK 3D7T 3D7U 3EAC 3EAZ
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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