LAYN and PLPP6

Data Source:
BioGRID (two hybrid)

		LAYN	PLPP6
Description		layilin	phospholipid phosphatase 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ruffle Focal Adhesion Cell Surface Integral Component Of Membrane	Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	Hyaluronic Acid Binding Carbohydrate Binding	Protein Binding Hydrolase Activity Sphingosine-1-phosphate Phosphatase Activity Lipid Phosphatase Activity
	Biological Process		Cholesterol Biosynthetic Process Phospholipid Dephosphorylation
Pathways			Cholesterol biosynthesis
Drugs		Hyaluronic acid
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406 29785011) Asthma ( 30929738) Asthma (adult onset) ( 30929738) Asthma or allergic disease (pleiotropy) ( 29785011) Bipolar disorder ( 31043756) Fish- and plant-related diet ( 32066663) Obesity-related traits ( 23251661) Oily fish consumption ( 32066663) Pork consumption ( 32066663)
Interacting Genes		6 interacting genes: DEFB121 GIMAP5 IGFBP5 MFSD11 PLPP6 RHOU	57 interacting genes: AMIGO1 AQP6 AQP8 BTN2A1 BTNL9 C16orf92 CD79A CIAO2A CLDN15 CLDN9 CLEC4M CLN5 COMT CREB3L1 EBP FAM174A FAM209A FAM210B FKBP7 FNDC9 FXYD3 GJB5 GKN1 GORAB GPX8 HSH2D IL10RA IL13RA2 KASH5 LAYN LDLRAD1 MMGT1 MS4A3 MUC1 NCR3LG1 PDGFRA PDZK1IP1 PHACTR3 PRLR PVR RETREG3 RNF170 RNF5 SEC11C SHISAL1 SIGLEC12 SLC7A14 SMAGP SOCS4 SSMEM1 STX1A SYNE4 SYNPR TMEM106C TMIE TNFRSF10D VSIR
Entrez ID		143903	403313
HPRD ID		17299	17397
Ensembl ID		ENSG00000204381	ENSG00000205808
Uniprot IDs		B4DDS5 Q6UX15	Q8IY26
PDB IDs
Enriched GO Terms of Interacting Partners?
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