KRTAP13-1 and COL8A1

Data Source:
BioGRID (two hybrid)

		KRTAP13-1	COL8A1
Description		keratin associated protein 13-1	collagen type VIII alpha 1 chain
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament	Extracellular Region Collagen Type VIII Trimer Extracellular Space Endoplasmic Reticulum Lumen Extracellular Matrix Collagen-containing Extracellular Matrix
	Molecular Function		Extracellular Matrix Structural Constituent Protein Binding Extracellular Matrix Structural Constituent Conferring Tensile Strength
	Biological Process	Keratinization	Angiogenesis Cell Adhesion Positive Regulation Of Cell-substrate Adhesion Extracellular Matrix Organization Endodermal Cell Differentiation Camera-type Eye Morphogenesis Epithelial Cell Proliferation
Pathways		Keratinization	Collagen degradation Collagen degradation Collagen biosynthesis and modifying enzymes Assembly of collagen fibrils and other multimeric structures Integrin cell surface interactions Collagen chain trimerization
Drugs
Diseases
GWAS		Treatment resistant depression ( 30468137)	Advanced age-related macular degeneration ( 26691988) Age-related macular degeneration ( 20385826 23455636) Axial length ( 24144296) Childhood ear infection ( 27182965) Cleft lip with or without cleft palate ( 28054174) Nonsyndromic cleft lip with cleft palate ( 28232668) Optic cup area ( 25631615 31798171 28073927) Optic disc area ( 31798171 28073927) Refractive error ( 32231278) Superior frontal gyrus grey matter volume ( 25335168) Vertical cup-disc ratio ( 31798171 25241763 28073927)
Interacting Genes		43 interacting genes: ARMC7 ATXN1L BAG4 BANF2 BCL6 CFAP206 CHRD COL8A1 CRACR2A FAM221B GLRX3 KLHL38 KRT34 KRTAP10-3 KRTAP10-5 KRTAP12-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LONRF1 MAPKBP1 MEIS2 NEK6 NMUR2 NOXA1 OTX1 PITX1 POU4F2 PROP1 PRR13 PSPC1 RANBP3 RBPMS RIN1 SCAMP1 STK16 TBC1D10C TBX6 TEKT4 TNS2 UBQLN2 VENTX YTHDF1	78 interacting genes: ADAMTSL4 ARMC5 BPIFA1 C11orf1 C19orf54 C22orf39 C9orf24 CCN3 CEP55 CIDEB COL8A2 CREB5 CYSRT1 DPEP2NB EFEMP2 FAM86C1P FBLN2 FBXO34 FRS3 GLRX3 GSC2 HOXA1 INCA1 ITGA1 ITGA2 KLHL12 KLHL20 KPRP KRT37 KRT40 KRT82 KRTAP1-3 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP12-3 KRTAP13-1 KRTAP13-3 KRTAP19-2 KRTAP19-5 KRTAP19-7 KRTAP26-1 KRTAP3-2 KRTAP4-12 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-2 KRTAP6-3 KRTAP9-2 KRTAP9-3 LIMS1 MAJIN NADSYN1 NBPF19 NOTCH2NLA OTX1 PLSCR3 POF1B POU4F2 PPARA RBPMS REL RGS20 RHBDD2 SLC35A2 SP4 SPATA8 SPRY4 SSC4D TRIM35 UBQLN2 UBQLN4 VAC14 WFDC5 YPEL3 ZNF774 ZNHIT1
Entrez ID		140258	1295
HPRD ID		10570	00372
Ensembl ID		ENSG00000198390	ENSG00000144810
Uniprot IDs		Q8IUC0	P27658
PDB IDs
Enriched GO Terms of Interacting Partners?
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