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COL8A1 and KRTAP10-3
Data Source:
BioGRID
(two hybrid)
COL8A1
KRTAP10-3
Description
collagen type VIII alpha 1 chain
keratin associated protein 10-3
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Collagen Type VIII Trimer
Extracellular Space
Endoplasmic Reticulum Lumen
Extracellular Matrix
Collagen-containing Extracellular Matrix
Cytosol
Keratin Filament
Molecular Function
Extracellular Matrix Structural Constituent
Protein Binding
Extracellular Matrix Structural Constituent Conferring Tensile Strength
Biological Process
Angiogenesis
Cell Adhesion
Positive Regulation Of Cell-substrate Adhesion
Extracellular Matrix Organization
Endodermal Cell Differentiation
Camera-type Eye Morphogenesis
Epithelial Cell Proliferation
Keratinization
Pathways
Collagen degradation
Collagen degradation
Collagen biosynthesis and modifying enzymes
Assembly of collagen fibrils and other multimeric structures
Integrin cell surface interactions
Collagen chain trimerization
Keratinization
Drugs
Diseases
GWAS
Advanced age-related macular degeneration (
26691988
)
Age-related macular degeneration (
20385826
23455636
)
Axial length (
24144296
)
Childhood ear infection (
27182965
)
Cleft lip with or without cleft palate (
28054174
)
Nonsyndromic cleft lip with cleft palate (
28232668
)
Optic cup area (
25631615
31798171
28073927
)
Optic disc area (
31798171
28073927
)
Refractive error (
32231278
)
Superior frontal gyrus grey matter volume (
25335168
)
Vertical cup-disc ratio (
31798171
25241763
28073927
)
Interacting Genes
78 interacting genes:
ADAMTSL4
ARMC5
BPIFA1
C11orf1
C19orf54
C22orf39
C9orf24
CCN3
CEP55
CIDEB
COL8A2
CREB5
CYSRT1
DPEP2NB
EFEMP2
FAM86C1P
FBLN2
FBXO34
FRS3
GLRX3
GSC2
HOXA1
INCA1
ITGA1
ITGA2
KLHL12
KLHL20
KPRP
KRT37
KRT40
KRT82
KRTAP1-3
KRTAP10-3
KRTAP10-7
KRTAP10-8
KRTAP12-3
KRTAP13-1
KRTAP13-3
KRTAP19-2
KRTAP19-5
KRTAP19-7
KRTAP26-1
KRTAP3-2
KRTAP4-12
KRTAP5-6
KRTAP5-7
KRTAP5-9
KRTAP6-2
KRTAP6-3
KRTAP9-2
KRTAP9-3
LIMS1
MAJIN
NADSYN1
NBPF19
NOTCH2NLA
OTX1
PLSCR3
POF1B
POU4F2
PPARA
RBPMS
REL
RGS20
RHBDD2
SLC35A2
SP4
SPATA8
SPRY4
SSC4D
TRIM35
UBQLN2
UBQLN4
VAC14
WFDC5
YPEL3
ZNF774
ZNHIT1
293 interacting genes:
ACY3
ADAMTSL3
ADAMTSL4
ADAMTSL5
AEN
ALDH3B1
ALPI
ALPP
AMMECR1
AP1M1
AQP1
AREG
AVPI1
AXIN1
B4GALT7
BAHD1
BCL6B
BMP7
BMS1P1
BRME1
BUD31
BYSL
C10orf62
C22orf39
CARD9
CARHSP1
CATIP
CATSPER1
CBX2
CCDC26
CCER1
CD164
CD300A
CD300LG
CDK5R1
CERK
CHIC2
CHRD
CHRNG
CLDN2
CLK3
CLK4
COL8A1
CREB5
CST2
CST9L
CTNNBIP1
CTRC
CXCL16
DAAM2
DDX43
DDX6
DERL2
DHRS1
DHX57
DMRT3
DNAL4
DOCK2
EFNA3
EGFL8
ELOA
FAM124B
FAM161A
FAM27E3
FAM71E2
FAM74A4
FAM76B
FARS2
FBXL18
FBXW5
FOXB1
FZD9
GABARAPL1
GATA2
GEM
GFOD1
GIP
GLIDR
GLIPR2
GLP1R
GLRX3
GNE
GNMT
GOLGA8EP
GPRIN2
GSTP1
GTF3C5
H2AW
HBG1
HBZ
HHEX
HNRNPLL
HOXA1
HPCAL1
HSBP1
HSD3B7
HSPD1
HYAL2
IGSF8
IL2RG
INPP5D
IQUB
IWS1
JOSD1
KAT5
KCNK1
KIAA0040
KIF9
KLHL38
KLK15
KLK8
KRT83
KRTAP10-1
KRTAP10-5
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP12-1
KRTAP13-1
KRTAP26-1
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP4-7
KRTAP5-6
KRTAP5-9
KRTAP9-2
LCE1B
LCE2A
LCE3C
LCE3E
LIMS2
LINC00636
LINC01588
LMF2
LMNA
LUZP4
LYVE1
MAPKBP1
MEOX2
MOBP
MPP3
MRPL40
MXI1
NAA10
NAB2
NAXD
NDUFAF3
NECTIN2
NECTIN3
NID2
NLK
NOTCH2NLA
NPBWR2
NPDC1
NPPB
NUBP2
NUDCD3
NUFIP2
OLFM2
OPCML
OTX1
P2RY6
PCED1A
PCSK5
PDE9A
PDIA5
PGAP2
PGAP6
PGLS
PIGS
PIN1
PKD2
PLSCR1
POLL
PPARD
PRKAA2
PRKAB2
PRKAG1
PRPF31
PTGDS
PTGER3
PTPMT1
PTPRH
PVR
QPRT
R3HDM2
RAB7A
RAMP3
RHNO1
RNF175
RPS19BP1
RPS28
RPUSD3
RTN4RL1
SCNM1
SDC3
SDCBP
SELENOM
SERF2
SHFL
SLC15A3
SLC23A1
SLC25A10
SLC25A48
SLC35A2
SLC43A2
SLC6A20
SMCO4
SMCP
SMOC1
SNAI1
SNHG11
SPACA9
SPATA3
SPATA8
SPG7
SPINK2
SPRY1
SPRY2
STK16
TBC1D23
TEAD4
TEDC2
THAP10
THAP7
TINAGL1
TLE5
TMEM106C
TNFRSF6B
TNIP3
TNK2
TNP2
TNS2
TRIM42
TRPV6
TTC23
TXNDC5
TYMSOS
TYRO3
UCP2
UNC45A
UTP23
VPS11
WFDC10B
WIF1
WT1
XCL1
YIPF3
ZBTB24
ZBTB9
ZFYVE21
ZFYVE26
ZMYND10
ZNF101
ZNF124
ZNF136
ZNF138
ZNF155
ZNF165
ZNF20
ZNF202
ZNF23
ZNF250
ZNF26
ZNF264
ZNF266
ZNF32
ZNF417
ZNF433
ZNF439
ZNF446
ZNF461
ZNF490
ZNF559
ZNF564
ZNF572
ZNF578
ZNF581
ZNF587
ZNF625
ZNF670
ZNF679
ZNF688
ZNF697
ZNF699
ZNF763
ZNF786
ZNF79
ZNF792
ZNRF2P1
ZSCAN21
ZSCAN26
Entrez ID
1295
386682
HPRD ID
00372
11189
Ensembl ID
ENSG00000144810
ENSG00000212935
Uniprot IDs
P27658
P60369
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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