COL8A1 and KRTAP13-3

Data Source:
BioGRID (two hybrid)

		COL8A1	KRTAP13-3
Description		collagen type VIII alpha 1 chain	keratin associated protein 13-3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Type VIII Trimer Extracellular Space Endoplasmic Reticulum Lumen Extracellular Matrix Collagen-containing Extracellular Matrix	Cytosol Intermediate Filament
	Molecular Function	Extracellular Matrix Structural Constituent Protein Binding Extracellular Matrix Structural Constituent Conferring Tensile Strength	Protein Binding
	Biological Process	Angiogenesis Cell Adhesion Positive Regulation Of Cell-substrate Adhesion Extracellular Matrix Organization Endodermal Cell Differentiation Camera-type Eye Morphogenesis Epithelial Cell Proliferation	Keratinization
Pathways		Collagen degradation Collagen degradation Collagen biosynthesis and modifying enzymes Assembly of collagen fibrils and other multimeric structures Integrin cell surface interactions Collagen chain trimerization	Keratinization
Drugs
Diseases
GWAS		Advanced age-related macular degeneration ( 26691988) Age-related macular degeneration ( 20385826 23455636) Axial length ( 24144296) Childhood ear infection ( 27182965) Cleft lip with or without cleft palate ( 28054174) Nonsyndromic cleft lip with cleft palate ( 28232668) Optic cup area ( 25631615 31798171 28073927) Optic disc area ( 31798171 28073927) Refractive error ( 32231278) Superior frontal gyrus grey matter volume ( 25335168) Vertical cup-disc ratio ( 31798171 25241763 28073927)
Interacting Genes		78 interacting genes: ADAMTSL4 ARMC5 BPIFA1 C11orf1 C19orf54 C22orf39 C9orf24 CCN3 CEP55 CIDEB COL8A2 CREB5 CYSRT1 DPEP2NB EFEMP2 FAM86C1P FBLN2 FBXO34 FRS3 GLRX3 GSC2 HOXA1 INCA1 ITGA1 ITGA2 KLHL12 KLHL20 KPRP KRT37 KRT40 KRT82 KRTAP1-3 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP12-3 KRTAP13-1 KRTAP13-3 KRTAP19-2 KRTAP19-5 KRTAP19-7 KRTAP26-1 KRTAP3-2 KRTAP4-12 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-2 KRTAP6-3 KRTAP9-2 KRTAP9-3 LIMS1 MAJIN NADSYN1 NBPF19 NOTCH2NLA OTX1 PLSCR3 POF1B POU4F2 PPARA RBPMS REL RGS20 RHBDD2 SLC35A2 SP4 SPATA8 SPRY4 SSC4D TRIM35 UBQLN2 UBQLN4 VAC14 WFDC5 YPEL3 ZNF774 ZNHIT1	68 interacting genes: ATG9A ATXN1 C14orf119 C1orf109 CCDC102B CCDC120 CCDC57 CLIC3 COL8A1 CRYBA1 CRYBA2 CYSRT1 DTX2 EFEMP2 FAH FOXH1 GATA2 GNE GPANK1 GPSM3 GUCD1 HEXIM2 HOXA1 HOXC8 HSD3B7 KCTD7 KCTD9 KPRP KRT83 KRTAP10-1 KRTAP10-11 KRTAP12-3 KRTAP3-1 KRTAP3-2 KRTAP5-11 KRTAP5-6 KRTAP9-2 KRTAP9-3 LNX1 LONRF1 MGAT5B MLX NBPF19 NEK6 NOTCH2NLA OTX1 PAX9 PCSK5 POU4F2 R3HDM2 RBPMS RUNX1T1 SLIT1 SMARCC1 SPAG8 TCP11 TEKT4 TLE5 TLX3 TOLLIP TRIM59 TRIM68 TSSK3 UBL5 VWC2 ZNF319 ZNF330 ZNF414
Entrez ID		1295	337960
HPRD ID		00372	11202
Ensembl ID		ENSG00000144810	ENSG00000240432
Uniprot IDs		P27658	Q3SY46
PDB IDs
Enriched GO Terms of Interacting Partners?
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