KRTAP13-1 and NOXA1

Data Source:
BioGRID (two hybrid)

		KRTAP13-1	NOXA1
Description		keratin associated protein 13-1	NADPH oxidase activator 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament	Cytosol NADPH Oxidase Complex
	Molecular Function		Protein Binding Superoxide-generating NADPH Oxidase Activator Activity SH3 Domain Binding Enzyme Binding Small GTPase Binding
	Biological Process	Keratinization	Superoxide Metabolic Process Regulation Of Hydrogen Peroxide Metabolic Process Superoxide Anion Generation Regulation Of Catalytic Activity Regulation Of Respiratory Burst
Pathways		Keratinization	RHO GTPases Activate NADPH Oxidases WNT5:FZD7-mediated leishmania damping
Drugs
Diseases
GWAS		Treatment resistant depression ( 30468137)	Response to fenofibrate (total cholesterol levels) ( 27002377)
Interacting Genes		43 interacting genes: ARMC7 ATXN1L BAG4 BANF2 BCL6 CFAP206 CHRD COL8A1 CRACR2A FAM221B GLRX3 KLHL38 KRT34 KRTAP10-3 KRTAP10-5 KRTAP12-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LONRF1 MAPKBP1 MEIS2 NEK6 NMUR2 NOXA1 OTX1 PITX1 POU4F2 PROP1 PRR13 PSPC1 RANBP3 RBPMS RIN1 SCAMP1 STK16 TBC1D10C TBX6 TEKT4 TNS2 UBQLN2 VENTX YTHDF1	57 interacting genes: ANKRD55 C19orf54 C9orf24 CACNA1A CEP70 CFP CRYBA1 CTDSP1 CYSRT1 DCLRE1B DDAH2 DUSP4 EP300 FAT1 GATAD2B IL16 KCTD15 KRTAP13-1 KRTAP15-1 KRTAP19-4 KRTAP19-7 KRTAP8-1 LASP1 LMO2 MAPK1 MAPK11 METTL27 MORN3 MYLIP NAA10 NADSYN1 NCF1 NDUFAB1 NOX1 NOXO1 PFDN5 PLA2G10 PRKACA PRKCA PRKCG QARS1 RAC1 RAC2 REL RIMBP3 RIMBP3C SMUG1 TCF19 TCF4 TGS1 TRAF2 TRIM23 UBAP2 WDR83 ZC2HC1C ZNF474 ZNF620
Entrez ID		140258	10811
HPRD ID		10570	17644
Ensembl ID		ENSG00000198390	ENSG00000188747
Uniprot IDs		Q8IUC0	Q86UR1
PDB IDs
Enriched GO Terms of Interacting Partners?
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