CREBL2 and CD27

Data Source:
BioGRID (affinity chromatography technology)

		CREBL2	CD27
Description		cAMP responsive element binding protein like 2	CD27 molecule
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding	Transmembrane Signaling Receptor Activity Protein Binding Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Cell Cycle Signal Transduction Cell Differentiation Positive Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Fat Cell Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Glucose Import Positive Regulation Of Lipid Biosynthetic Process Protein Stabilization	Cell Surface Receptor Signaling Pathway Immunoglobulin Mediated Immune Response Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Response To Ethanol Positive Regulation Of B Cell Differentiation Positive Regulation Of T Cell Differentiation Positive Regulation Of JNK Cascade Negative Regulation Of T Cell Apoptotic Process Extrinsic Apoptotic Signaling Pathway Positive Regulation Of NIK/NF-kappaB Signaling
Pathways			TNFs bind their physiological receptors
Drugs
Diseases
GWAS		Height ( 31562340) Midgestational circulating levels of PBDEs (fetal genetic effect) ( 28235828) Response to fenofibrate (HDL cholesterol levels) ( 27002377) Systemic lupus erythematosus ( 23273568)	Crohn's disease ( 26192919)
Interacting Genes		5 interacting genes: CREBRF DDIT3 DNMT3L PKNOX2 UBE2I	8 interacting genes: ACTN2 CD70 CIB1 SIVA1 TRAF2 TRAF3 TRAF5 UHRF2
Entrez ID		1389	939
HPRD ID		07541	01723
Ensembl ID		ENSG00000111269	ENSG00000139193
Uniprot IDs		O60519	P26842
PDB IDs			5TL5 5TLJ 5TLK
Enriched GO Terms of Interacting Partners?
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