PM20D2 and TDO2

		PM20D2	TDO2
Description		peptidase M20 domain containing 2	tryptophan 2,3-dioxygenase
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm	Cytosol
	Molecular Function	Protein Binding Dipeptidase Activity Identical Protein Binding Para-aminobenzoyl-glutamate Hydrolase Activity	Tryptophan 2,3-dioxygenase Activity Protein Binding Amino Acid Binding Oxygen Binding Heme Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Proteolysis Regulation Of Cellular Protein Metabolic Process Folic Acid Catabolic Process	Tryptophan Catabolic Process Tryptophan Catabolic Process To Kynurenine Tryptophan Catabolic Process To Acetyl-CoA Protein Homotetramerization Response To Nitroglycerin
Pathways			Tryptophan catabolism
Drugs
Diseases
GWAS		Blood metabolite levels ( 24816252)	Blood metabolite levels ( 24816252) Manganese levels ( 26025379) Speech perception in dyslexia ( 19786962)
Interacting Genes		23 interacting genes: CERT1 CNNM3 DALRD3 DDIT4L DNAJC11 EPDR1 HAPLN2 KEL KRT75 KRTAP26-1 MEOX1 MYOZ3 NAA80 POU6F2 PSMA1 REL RGS12 RP2 RUSC1 SAXO1 SIVA1 TAPBPL TDO2	20 interacting genes: ASMTL DPM1 EIF4E KDM1A LMNA LNX1 MEOX2 MOB1A MOB3C NGB NMNAT1 NR1D1 PICK1 PM20D2 PRMT6 PSMA1 REL SDCBP SDCBP2 ZFYVE26
Entrez ID		135293	6999
HPRD ID		16473	01847
Ensembl ID		ENSG00000146281	ENSG00000151790
Uniprot IDs		Q8IYS1	P48775
PDB IDs			4PW8 5TI9 5TIA 6A4I 6PYY 6PYZ 6VBN
Enriched GO Terms of Interacting Partners?
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