PM20D2 and RGS12

Data Source:
BioGRID (two hybrid)

		PM20D2	RGS12
Description		peptidase M20 domain containing 2	regulator of G protein signaling 12
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm	Condensed Nuclear Chromosome Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Plasma Membrane Nuclear Matrix Dendrite Synapse
	Molecular Function	Protein Binding Dipeptidase Activity Identical Protein Binding Para-aminobenzoyl-glutamate Hydrolase Activity	GTPase Activity GTPase Activator Activity Protein Binding GTPase Regulator Activity
	Biological Process	Proteolysis Regulation Of Cellular Protein Metabolic Process Folic Acid Catabolic Process	G Protein-coupled Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Signal Transduction Positive Regulation Of GTPase Activity
Pathways			G alpha (i) signalling events G alpha (i) signalling events
Drugs
Diseases
GWAS		Blood metabolite levels ( 24816252)	Adult body size ( 32376654) Blood protein levels ( 28240269) Coronary artery disease ( 29212778) Creatinine levels ( 29403010) Estimated glomerular filtration rate ( 31015462 30604766) Glomerular filtration rate ( 29403010) Hepatocyte growth factor levels ( 25998175) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (HMG CoA reductase inhibitors) ( 31015401) Platelet count ( 29403010) Serum albumin level ( 29403010) Total cholesterol levels ( 29403010) Tuberculosis ( 29036319) Worry too long after an embarrassing experience ( 29500382)
Interacting Genes		23 interacting genes: CERT1 CNNM3 DALRD3 DDIT4L DNAJC11 EPDR1 HAPLN2 KEL KRT75 KRTAP26-1 MEOX1 MYOZ3 NAA80 POU6F2 PSMA1 REL RGS12 RP2 RUSC1 SAXO1 SIVA1 TAPBPL TDO2	17 interacting genes: ARAF CACNA1B CXCR2 EEF1A1 GNAI1 GNAI2 GNAI3 GRM2 GRM5 HRAS MAP2K2 MTNR1A NPY2R PLCB1 PLCB3 PM20D2 YWHAG
Entrez ID		135293	6002
HPRD ID		16473	03943
Ensembl ID		ENSG00000146281	ENSG00000159788
Uniprot IDs		Q8IYS1	O14924
PDB IDs			2EBZ 2KV8
Enriched GO Terms of Interacting Partners?
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