TDO2 and ASMTL

Data Source:
BioGRID (two hybrid, two hybrid, affinity chromatography technology, two hybrid, two hybrid)
HPRD (two hybrid)

		TDO2	ASMTL
Description		tryptophan 2,3-dioxygenase	acetylserotonin O-methyltransferase like
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GO Annotations	Cellular Component	Cytosol	Cytosol
	Molecular Function	Tryptophan 2,3-dioxygenase Activity Protein Binding Amino Acid Binding Oxygen Binding Heme Binding Identical Protein Binding Metal Ion Binding	Molecular_function Protein Binding O-methyltransferase Activity NADH Pyrophosphatase Activity DTTP Diphosphatase Activity Nucleoside-triphosphate Diphosphatase Activity
	Biological Process	Tryptophan Catabolic Process Tryptophan Catabolic Process To Kynurenine Tryptophan Catabolic Process To Acetyl-CoA Protein Homotetramerization Response To Nitroglycerin	Biological_process Nucleotide Metabolic Process Methylation
Pathways		Tryptophan catabolism
Drugs
Diseases
GWAS		Blood metabolite levels ( 24816252) Manganese levels ( 26025379) Speech perception in dyslexia ( 19786962)
Interacting Genes		20 interacting genes: ASMTL DPM1 EIF4E KDM1A LMNA LNX1 MEOX2 MOB1A MOB3C NGB NMNAT1 NR1D1 PICK1 PM20D2 PRMT6 PSMA1 REL SDCBP SDCBP2 ZFYVE26	10 interacting genes: APP GORASP2 HLA-DRB4 KRT31 KRT34 KRT40 PNMA1 REL TDO2 ZNF655
Entrez ID		6999	8623
HPRD ID		01847	02156
Ensembl ID		ENSG00000151790	ENSG00000169093
Uniprot IDs		P48775	B3KM43 O95671
PDB IDs		4PW8 5TI9 5TIA 6A4I 6PYY 6PYZ 6VBN	2P5X
Enriched GO Terms of Interacting Partners?
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