IRAK1BP1 and USP20

Data Source:
BioGRID (two hybrid)

		IRAK1BP1	USP20
Description		interleukin 1 receptor associated kinase 1 binding protein 1	ubiquitin specific peptidase 20
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Cytoplasm Centrosome Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	G Protein-coupled Receptor Binding Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Zinc Ion Binding
	Biological Process	Immune Response I-kappaB Kinase/NF-kappaB Signaling	Ubiquitin-dependent Protein Catabolic Process Endocytosis Regulation Of G Protein-coupled Receptor Signaling Pathway Protein Deubiquitination Protein Phosphopantetheinylation Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination
Pathways			Ub-specific processing proteases
Drugs
Diseases
GWAS		Blood pressure measurement (high sodium and potassium intervention) ( 24165912) Blood pressure measurement (high sodium intervention) ( 24165912) Blood pressure measurement (low sodium intervention) ( 24165912) Cadmium levels ( 26025379) Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Late-onset Alzheimer's disease ( 27770636) LDL cholesterol levels x loop diuretics use interaction ( 31806883) Macular thickness ( 30535121) SjÃ¶gren's syndrome ( 24097067)	Metabolite levels ( 23823483)
Interacting Genes		10 interacting genes: IRAK1 MISP PHF1 PRKAB2 RELA RIPPLY1 SCNM1 TFCP2 USP20 ZNF410	69 interacting genes: AGR2 ALAS1 APBA2 ARID5A ASCL1 ATP6V1G2 BEND5 BEND7 BHLHB9 BRPF1 C1QTNF2 CCNL2 CDK2AP1 CLSPN CTAG1A CTAG1B DIO2 ENKD1 EPAS1 FATE1 FTO GPRASP2 GTF2IRD1 HAND2 HIF1A HSF2BP IHO1 IRAK1BP1 ITGB3BP KLHL20 LMNA MAGEA11 MAPK6 MBD3L1 MCCD1 MDFI MEOX2 MRPL28 PBX4 PJA1 PLA2G2A PRKACA PRKCI RAD17 RSPO4 SAMD12 SPRY2 SRGAP2B STING1 TNNI1 TRIB3 TRIM23 TTC19 TTC23L ULK1 USP15 USP21 USP28 VAPA VAPB VAX1 VHL WASHC1 ZBTB10 ZFYVE26 ZNF343 ZNF408 ZNF620 ZXDB
Entrez ID		134728	10868
HPRD ID		17157	07505
Ensembl ID		ENSG00000146243	ENSG00000136878
Uniprot IDs		Q5VVH5	Q9Y2K6
PDB IDs			6KCZ
Enriched GO Terms of Interacting Partners?
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