TRIM71 and MIR1-2

Data Source:
BioGRID (unspecified method)

		TRIM71	MIR1-2
Description		tripartite motif containing 71	microRNA 1-2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	P-body
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Translation Repressor Activity MiRNA Binding Ubiquitin Protein Ligase Activity
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Protein Polyubiquitination Neural Tube Closure Fibroblast Growth Factor Receptor Signaling Pathway MiRNA Metabolic Process Posttranscriptional Regulation Of Gene Expression Negative Regulation Of Translation Neural Tube Development Production Of MiRNAs Involved In Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein Autoubiquitination Regulation Of Gene Silencing By MiRNA 3'-UTR-mediated MRNA Destabilization Stem Cell Proliferation Regulation Of Neural Precursor Cell Proliferation Positive Regulation Of Gene Silencing By MiRNA	Gene Silencing By MiRNA
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Asthma ( 31959851) Asthma (childhood onset) ( 31036433) Heel bone mineral density ( 30598549) Metabolite levels ( 23823483) Multiple sclerosis ( 31604244) Pulmonary function ( 21946350) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		11 interacting genes: LIN28B MIR1-1 MIR1-2 MIR100 MIR155 MIR15A MIR18B MIR25 MIR29A MIR29B1 MIRLET7F2	78 interacting genes: ADARB1 APOBEC3B C1QBP CPSF1 CPSF7 DARS1 DDX1 DDX21 DDX3X DDX49 DHX36 DHX37 EDC4 EIF2AK2 EPRS1 FAM98A FUS GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 NOL6 NONO NUDT21 P3H1 PATL1 PDCD11 PLOD1 PRMT1 PTBP1 PTBP3 PUF60 PUM1 QARS1 RARS1 RBM14 RBM4 RBMS2 RTCB SF3B1 SF3B2 SF3B3 SFPQ STRBP SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B TRIM71 UPF1 UTP20 YBX1 YBX2 YBX3 ZNF346
Entrez ID		131405	406905
HPRD ID		19029
Ensembl ID		ENSG00000206557	ENSG00000284453
Uniprot IDs		Q2Q1W2
PDB IDs
Enriched GO Terms of Interacting Partners?
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