MIR1-2 and UTP20

Data Source:
BioGRID (unspecified method)

		MIR1-2	UTP20
Description		microRNA 1-2	UTP20 small subunit processome component
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleoplasm Nucleolus Cytoplasm Plasma Membrane 90S Preribosome Preribosome, Small Subunit Precursor Small-subunit Processome
	Molecular Function		RNA Binding Protein Binding
	Biological Process	Gene Silencing By MiRNA	Endonucleolytic Cleavage In ITS1 To Separate SSU-rRNA From 5.8S RRNA And LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Endonucleolytic Cleavage To Generate Mature 5'-end Of SSU-rRNA From (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Endonucleolytic Cleavage In 5'-ETS Of Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RRNA Processing Negative Regulation Of Cell Population Proliferation
Pathways			rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS			Alcohol dependence (age at onset) ( 24962325) Brain structure (hippocampal volume) ( 20197096) Health literacy ( 31250787)
Interacting Genes		78 interacting genes: ADARB1 APOBEC3B C1QBP CPSF1 CPSF7 DARS1 DDX1 DDX21 DDX3X DDX49 DHX36 DHX37 EDC4 EIF2AK2 EPRS1 FAM98A FUS GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 NOL6 NONO NUDT21 P3H1 PATL1 PDCD11 PLOD1 PRMT1 PTBP1 PTBP3 PUF60 PUM1 QARS1 RARS1 RBM14 RBM4 RBMS2 RTCB SF3B1 SF3B2 SF3B3 SFPQ STRBP SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B TRIM71 UPF1 UTP20 YBX1 YBX2 YBX3 ZNF346	72 interacting genes: MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I PPP1R26
Entrez ID		406905	27340
HPRD ID			09928
Ensembl ID		ENSG00000284453	ENSG00000120800
Uniprot IDs			O75691
PDB IDs
Enriched GO Terms of Interacting Partners?
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