TRIM71 and MIR100

Data Source:
BioGRID (unspecified method)

		TRIM71	MIR100
Description		tripartite motif containing 71	microRNA 100
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	P-body	Extracellular Space Extracellular Vesicle
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Translation Repressor Activity MiRNA Binding Ubiquitin Protein Ligase Activity	MRNA Binding Involved In Posttranscriptional Gene Silencing
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Protein Polyubiquitination Neural Tube Closure Fibroblast Growth Factor Receptor Signaling Pathway MiRNA Metabolic Process Posttranscriptional Regulation Of Gene Expression Negative Regulation Of Translation Neural Tube Development Production Of MiRNAs Involved In Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein Autoubiquitination Regulation Of Gene Silencing By MiRNA 3'-UTR-mediated MRNA Destabilization Stem Cell Proliferation Regulation Of Neural Precursor Cell Proliferation Positive Regulation Of Gene Silencing By MiRNA	Negative Regulation Of Interleukin-8 Production Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Negative Regulation Of Vascular Associated Smooth Muscle Cell Differentiation
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Asthma ( 31959851) Asthma (childhood onset) ( 31036433) Heel bone mineral density ( 30598549) Metabolite levels ( 23823483) Multiple sclerosis ( 31604244) Pulmonary function ( 21946350) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		11 interacting genes: LIN28B MIR1-1 MIR1-2 MIR100 MIR155 MIR15A MIR18B MIR25 MIR29A MIR29B1 MIRLET7F2	1 interacting genes: TRIM71
Entrez ID		131405	406892
HPRD ID		19029
Ensembl ID		ENSG00000206557	ENSG00000207994
Uniprot IDs		Q2Q1W2
PDB IDs
Enriched GO Terms of Interacting Partners?
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