COL17A1 and DST

Data Source:
HPRD (in vivo, two hybrid)

		COL17A1	DST
Description		collagen type XVII alpha 1 chain	dystonin
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Trimer Basement Membrane Extracellular Space Endoplasmic Reticulum Lumen Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Hemidesmosome Extracellular Matrix Collagen-containing Extracellular Matrix	Basement Membrane Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Endoplasmic Reticulum Membrane Cytosol Intermediate Filament Focal Adhesion Cell Cortex Basal Plasma Membrane Microtubule Cytoskeleton Membrane Integral Component Of Membrane Z Disc Hemidesmosome Cell Leading Edge Cytoplasmic Vesicle H Zone Microtubule Plus-end Axon Cytoplasm
	Molecular Function	Extracellular Matrix Structural Constituent Protein Binding Extracellular Matrix Structural Constituent Conferring Tensile Strength	Actin Binding Integrin Binding Structural Molecule Activity Calcium Ion Binding Protein Binding Microtubule Binding Protein C-terminus Binding Microtubule Plus-end Binding
	Biological Process	Cell-matrix Adhesion Epidermis Development Extracellular Matrix Organization Hemidesmosome Assembly Regulation Of Immune Response	Cytoskeleton Organization Cell Adhesion Integrin-mediated Signaling Pathway Retrograde Axonal Transport Response To Wounding Maintenance Of Cell Polarity Cytoplasmic Microtubule Organization Hemidesmosome Assembly Wound Healing Intermediate Filament Cytoskeleton Organization Cell Motility
Pathways		Collagen degradation Collagen biosynthesis and modifying enzymes Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Assembly of collagen fibrils and other multimeric structures Type I hemidesmosome assembly Collagen chain trimerization	Type I hemidesmosome assembly
Drugs
Diseases		Epidermolysis bullosa, junctional, including: Epidermolysis bullosa, junctional, Herlitz type (JEB-H); Epidermolysis bullosa, junctional, non-Herlitz type (JEB-nH); Epidermolysis bullosa, junctional, with pyloric atresia (JEB-PA)
GWAS		Cardiac hypertrophy ( 21348951)	Alzheimer disease and age of onset ( 26830138) Attention function in attention deficit hyperactive disorder ( 26174813) Cerebrospinal fluid clusterin levels ( 26545630) Daytime sleep phenotypes ( 27126917) Gout (normal type) ( 32238385) Heel bone mineral density ( 30598549) Mean spheric corpuscular volume ( 32888494) Menarche (age at onset) ( 25231870) Red blood cell count ( 32888494) Small cell lung carcinoma ( 28604730)
Interacting Genes		18 interacting genes: ACTN1 ACTN4 CLSTN1 CSTF2T CTNND1 DSP DST ITGA6 ITGB4 KRT18 LAD1 PLEC PLOD3 PNKP PPIL1 PPL UBQLN2 WHRN	37 interacting genes: ABI1 ANKRD1 APC C1QTNF9 CALM1 CDC5L CELSR3 CEP63 CLIP4 COL17A1 DCTN1 DISC1 DTNBP1 ECPAS ERBB2 ERBIN EXOC1 ITGB4 ITSN2 KIAA1549 KRT14 KRT5 LINC01554 MAPK6 MTNR1B MYBPC2 NFYC PAK2 PRKAB2 PRKD2 PTGER4 SH3BP5 SMAD9 SNAPIN TNIK TRAF3IP1 TULP3
Entrez ID		1308	667
HPRD ID		00223	00222
Ensembl ID		ENSG00000065618	ENSG00000151914
Uniprot IDs		Q9UMD9	B4DGY0 B4DSS9 E9PHM6 F6QMI7 Q03001 Q6P0N6
PDB IDs			3GJO
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?