DST and EXOC1

Data Source:
BioGRID (two hybrid)

		DST	EXOC1
Description		dystonin	exocyst complex component 1
Image			No pdb structure
GO Annotations	Cellular Component	Basement Membrane Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Endoplasmic Reticulum Membrane Cytosol Intermediate Filament Focal Adhesion Cell Cortex Basal Plasma Membrane Microtubule Cytoskeleton Membrane Integral Component Of Membrane Z Disc Hemidesmosome Cell Leading Edge Cytoplasmic Vesicle H Zone Microtubule Plus-end Axon Cytoplasm	Exocyst Cytoplasm Cytosol Plasma Membrane Membrane Perinuclear Region Of Cytoplasm Flemming Body Cytoplasmic Side Of Apical Plasma Membrane
	Molecular Function	Actin Binding Integrin Binding Structural Molecule Activity Calcium Ion Binding Protein Binding Microtubule Binding Protein C-terminus Binding Microtubule Plus-end Binding	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding
	Biological Process	Cytoskeleton Organization Cell Adhesion Integrin-mediated Signaling Pathway Retrograde Axonal Transport Response To Wounding Maintenance Of Cell Polarity Cytoplasmic Microtubule Organization Hemidesmosome Assembly Wound Healing Intermediate Filament Cytoskeleton Organization Cell Motility	Exocytosis Golgi To Plasma Membrane Transport Protein Transport Viral Process Regulation Of Macroautophagy Phosphatidylinositol-mediated Signaling Positive Regulation Of Protein Secretion Defense Response To Virus
Pathways		Type I hemidesmosome assembly	Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS		Alzheimer disease and age of onset ( 26830138) Attention function in attention deficit hyperactive disorder ( 26174813) Cerebrospinal fluid clusterin levels ( 26545630) Daytime sleep phenotypes ( 27126917) Gout (normal type) ( 32238385) Heel bone mineral density ( 30598549) Mean spheric corpuscular volume ( 32888494) Menarche (age at onset) ( 25231870) Red blood cell count ( 32888494) Small cell lung carcinoma ( 28604730)	Cerebrospinal P-tau181p levels ( 28247064) Cervical cancer ( 23817570) Daytime sleep phenotypes ( 27126917) Urinary albumin excretion ( 32277301) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		37 interacting genes: ABI1 ANKRD1 APC C1QTNF9 CALM1 CDC5L CELSR3 CEP63 CLIP4 COL17A1 DCTN1 DISC1 DTNBP1 ECPAS ERBB2 ERBIN EXOC1 ITGB4 ITSN2 KIAA1549 KRT14 KRT5 LINC01554 MAPK6 MTNR1B MYBPC2 NFYC PAK2 PRKAB2 PRKD2 PTGER4 SH3BP5 SMAD9 SNAPIN TNIK TRAF3IP1 TULP3	30 interacting genes: ATG14 CCDC88A CCDC93 CCHCR1 CCSER2 CDC5L CEP295 COLEC12 DISC1 DST KANSL1 KDM1A LUC7L2 MACF1 MTNR1A NUF2 NUP54 RALA RB1CC1 RESF1 RUBCN SFR1 SH3BP5 SNAPIN SPTAN1 SRGAP2 SYBU TRAF3IP1 TRIM9 TRIO
Entrez ID		667	55763
HPRD ID		00222	07615
Ensembl ID		ENSG00000151914	ENSG00000090989
Uniprot IDs		B4DGY0 B4DSS9 E9PHM6 F6QMI7 Q03001 Q6P0N6	A0A024RDA1 A1LT29 Q9NV70
PDB IDs		3GJO
Enriched GO Terms of Interacting Partners?
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