COL17A1 and CLSTN1

Data Source:
HPRD (two hybrid)

		COL17A1	CLSTN1
Description		collagen type XVII alpha 1 chain	calsyntenin 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Trimer Basement Membrane Extracellular Space Endoplasmic Reticulum Lumen Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Hemidesmosome Extracellular Matrix Collagen-containing Extracellular Matrix	Golgi Membrane Extracellular Region Nucleus Endoplasmic Reticulum Membrane Cell Surface Postsynaptic Membrane Postsynaptic Endosome Glutamatergic Synapse GABA-ergic Synapse Integral Component Of Postsynaptic Density Membrane Integral Component Of Spine Apparatus Membrane
	Molecular Function	Extracellular Matrix Structural Constituent Protein Binding Extracellular Matrix Structural Constituent Conferring Tensile Strength	Amyloid-beta Binding Calcium Ion Binding Protein Binding Kinesin Binding X11-like Protein Binding
	Biological Process	Cell-matrix Adhesion Epidermis Development Extracellular Matrix Organization Hemidesmosome Assembly Regulation Of Immune Response	Regulation Of Cell Growth Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Positive Regulation Of Synaptic Transmission Positive Regulation Of Synapse Assembly Regulation Of Synapse Maturation Neurotransmitter Receptor Transport To Postsynaptic Membrane Vesicle-mediated Transport In Synapse
Pathways		Collagen degradation Collagen biosynthesis and modifying enzymes Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Assembly of collagen fibrils and other multimeric structures Type I hemidesmosome assembly Collagen chain trimerization
Drugs
Diseases		Epidermolysis bullosa, junctional, including: Epidermolysis bullosa, junctional, Herlitz type (JEB-H); Epidermolysis bullosa, junctional, non-Herlitz type (JEB-nH); Epidermolysis bullosa, junctional, with pyloric atresia (JEB-PA)
GWAS		Cardiac hypertrophy ( 21348951)
Interacting Genes		18 interacting genes: ACTN1 ACTN4 CLSTN1 CSTF2T CTNND1 DSP DST ITGA6 ITGB4 KRT18 LAD1 PLEC PLOD3 PNKP PPIL1 PPL UBQLN2 WHRN	14 interacting genes: APBA2 APBB1 BAHCC1 COL17A1 KIF2A KLC1 KLC2 MCM3AP MDM2 PRNP SETDB1 SLK TOPBP1 TRIP12
Entrez ID		1308	22883
HPRD ID		00223	10837
Ensembl ID		ENSG00000065618	ENSG00000171603
Uniprot IDs		Q9UMD9	B4E3Q1 O94985
PDB IDs
Enriched GO Terms of Interacting Partners?
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