DST and TRAF3IP1

Data Source:
BioGRID (two hybrid)

		DST	TRAF3IP1
Description		dystonin	TRAF3 interacting protein 1
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GO Annotations	Cellular Component	Basement Membrane Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Endoplasmic Reticulum Membrane Cytosol Intermediate Filament Focal Adhesion Cell Cortex Basal Plasma Membrane Microtubule Cytoskeleton Membrane Integral Component Of Membrane Z Disc Hemidesmosome Cell Leading Edge Cytoplasmic Vesicle H Zone Microtubule Plus-end Axon Cytoplasm	Centrosome Cilium Axoneme Intraciliary Transport Particle B Ciliary Transition Zone Ciliary Basal Body Ciliary Tip Ciliary Base
	Molecular Function	Actin Binding Integrin Binding Structural Molecule Activity Calcium Ion Binding Protein Binding Microtubule Binding Protein C-terminus Binding Microtubule Plus-end Binding	Protein Binding Microtubule Binding
	Biological Process	Cytoskeleton Organization Cell Adhesion Integrin-mediated Signaling Pathway Retrograde Axonal Transport Response To Wounding Maintenance Of Cell Polarity Cytoplasmic Microtubule Organization Hemidesmosome Assembly Wound Healing Intermediate Filament Cytoskeleton Organization Cell Motility	Morphogenesis Of A Polarized Epithelium Kidney Development Negative Regulation Of Protein Phosphorylation Negative Regulation Of Protein-containing Complex Assembly Negative Regulation Of Type I Interferon Production Intraciliary Transport Involved In Cilium Assembly Intraciliary Transport Negative Regulation Of Defense Response To Virus Cilium Assembly Regulation Of Microtubule Cytoskeleton Organization
Pathways		Type I hemidesmosome assembly	Intraflagellar transport Intraflagellar transport
Drugs
Diseases
GWAS		Alzheimer disease and age of onset ( 26830138) Attention function in attention deficit hyperactive disorder ( 26174813) Cerebrospinal fluid clusterin levels ( 26545630) Daytime sleep phenotypes ( 27126917) Gout (normal type) ( 32238385) Heel bone mineral density ( 30598549) Mean spheric corpuscular volume ( 32888494) Menarche (age at onset) ( 25231870) Red blood cell count ( 32888494) Small cell lung carcinoma ( 28604730)	Chronotype ( 30696823) FEV1 ( 30804560) Intraocular pressure ( 29617998 29785010 30054594) Iris characteristics ( 21835309) Lung function (FEV1/FVC) ( 28166213 30804560) Metabolite levels ( 23823483) Morning person ( 30696823) Refractive astigmatism ( 30306274) Refractive error ( 32231278) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		37 interacting genes: ABI1 ANKRD1 APC C1QTNF9 CALM1 CDC5L CELSR3 CEP63 CLIP4 COL17A1 DCTN1 DISC1 DTNBP1 ECPAS ERBB2 ERBIN EXOC1 ITGB4 ITSN2 KIAA1549 KRT14 KRT5 LINC01554 MAPK6 MTNR1B MYBPC2 NFYC PAK2 PRKAB2 PRKD2 PTGER4 SH3BP5 SMAD9 SNAPIN TNIK TRAF3IP1 TULP3	29 interacting genes: ABI2 APP CCDC93 CCNA2 CDC5L DISC1 DMD DST DTNBP1 EXOC1 FRMD4A GOLGA4 IL13RA1 IMMT MACF1 OLFM1 SFR1 SGF29 SMC2 SMC3 SMC4 SNAP91 SPTBN1 TAB2 TRAF3 TRAF6 TRAK1 UBXN10 WAC
Entrez ID		667	26146
HPRD ID		00222	09571
Ensembl ID		ENSG00000151914	ENSG00000204104
Uniprot IDs		B4DGY0 B4DSS9 E9PHM6 F6QMI7 Q03001 Q6P0N6	Q8TDR0
PDB IDs		3GJO	2EQO
Enriched GO Terms of Interacting Partners?
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