ICA1L and RCOR3

Data Source:
BioGRID (two hybrid)

		ICA1L	RCOR3
Description		islet cell autoantigen 1 like	REST corepressor 3
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus	Histone Deacetylase Complex Nucleoplasm Transcription Regulator Complex Cytosol
	Molecular Function	Protein Binding Protein Domain Specific Binding	Transcription Corepressor Activity Protein Binding
	Biological Process	Regulation Of Transport	Regulation Of Transcription By RNA Polymerase II Histone Deacetylation Negative Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Heel bone mineral density ( 28869591) Ischemic stroke (small-vessel) ( 29531354) Mean platelet volume ( 32888494) Microalbuminuria ( 31511532) Non-lobar intracerebral hemorrhage (MTAG) ( 31430377) Platelet count ( 32888494) Spontaneous coronary artery dissection ( 32887874) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Urinary albumin excretion ( 30220432) Urinary albumin-to-creatinine ratio ( 31630189 31511532) White matter hyperintensities ( 32358547) White matter integrity (fractional anisotropy) ( 32358547)	Plateletcrit ( 32888494)
Interacting Genes		9 interacting genes: DPY30 GCC1 HGS KIFC3 KRT27 LMO2 MTDH RCOR3 TNPO3	74 interacting genes: ABI1 ANKRD11 APP BHLHB9 BORCS6 CBY2 CCDC102B CCDC106 CCHCR1 CDR2 CEP55 CEP63 CEP70 EFHC2 FAM81A FSD2 GKAP1 GLRX3 GOLGA2 GRIPAP1 GSE1 HAUS3 HMBOX1 HOOK2 HSF2BP ICA1L IKZF3 ING5 ISY1-RAB43 KDM1A KRT15 KRT18 KRT19 KRT24 KRT27 KRT31 KRT40 KRT75 LCA5 LHX3 LUZP4 LZTS2 MAGEA6 MCC MESD MID2 MIPOL1 MTUS2 NDUFB7 NECAB2 NINL NRDE2 NUTM1 PHF19 PHF21B PIH1D1 PRDM14 PTTG2 STN1 SUMO2 TFIP11 TRAF1 TRAF2 TRIM27 TRIM42 TRIM54 TSGA10 TULP3 TXLNA USHBP1 VAX1 YWHAQ ZNF383 ZNF688
Entrez ID		130026	55758
HPRD ID		12447	08338
Ensembl ID		ENSG00000163596	ENSG00000117625
Uniprot IDs		A0A024R3W3 Q8NDH6 Q96Q33	Q9P2K3
PDB IDs			4CZZ
Enriched GO Terms of Interacting Partners?
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