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COL8A2 and FAM209A
Data Source:
BioGRID
(two hybrid)
COL8A2
FAM209A
Description
collagen type VIII alpha 2 chain
family with sequence similarity 209 member A
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Collagen Trimer
Basement Membrane
Extracellular Space
Endoplasmic Reticulum Lumen
Extracellular Matrix
Collagen-containing Extracellular Matrix
Nucleus
Integral Component Of Membrane
Extracellular Exosome
Molecular Function
Extracellular Matrix Structural Constituent
Extracellular Matrix Structural Constituent Conferring Tensile Strength
Protein-macromolecule Adaptor Activity
Molecular_function
Protein Binding
Biological Process
Angiogenesis
Extracellular Matrix Organization
Camera-type Eye Morphogenesis
Epithelial Cell Proliferation
Cell-cell Adhesion
Biological_process
Pathways
Collagen degradation
Collagen degradation
Collagen biosynthesis and modifying enzymes
Assembly of collagen fibrils and other multimeric structures
Integrin cell surface interactions
Collagen chain trimerization
Drugs
Diseases
Posterior polymorphous corneal dystrophy (PPCD)
Fuchs corneal dystrophy (FECD); Fuchs endothelial corneal dystrophy
GWAS
Central corneal thickness (
32528159
29760442
)
Corneal structure (
23291589
)
Early spontaneous preterm birth (
31194736
)
Intraocular pressure (
29617998
29785010
31959993
)
Heschl's gyrus morphology (
25130324
)
Interacting Genes
18 interacting genes:
ARL13B
ATP6V0E1
BSND
COL8A1
CREB3L1
CYB5R3
DARS2
FAM209A
FNDC9
GPR152
GPX8
LMNA
MUC1
PEX12
PLEKHO1
SGTA
TFAM
TMX2
231 interacting genes:
-
ADGRE2
ADIPOQ
AGTRAP
AIG1
ALG8
ANKRD46
APMAP
APOC3
APOD
APOL2
AQP1
AQP2
AQP3
ARV1
ASGR1
ATP13A1
B4GALNT2
BDNF
BET1
BIK
BMP10
BNIP2
BNIP3
BTN2A2
C11orf24
C14orf180
C1GALT1
C2
C3orf52
C4orf3
CANT1
CCL4L2
CD53
CD59
CD81
CDIPT
CDS1
CDS2
CLCA4
CLDN19
CLDN2
CLDN4
CLDND2
CLEC4G
CLN6
CMTM7
CNIH1
CNPY3
COL4A5
COL8A2
COMT
CTRL
CTSA
CTXN3
CXCL16
CYB561D2
CYB5B
CYBC1
DEFB121
DEFB128
DNAJC30
DOLK
EBP
EMC6
EMD
ENTPD3
EOGT
ERG28
ERMP1
FA2H
FAM20B
FAM3C
FATE1
FCER1G
FDFT1
FIS1
FXYD3
GAST
GET3
GHITM
GIMAP1
GJB2
GKN1
GKN2
GOSR2
GPR108
GPR151
GPR37L1
GYPA
HACD2
HHATL
HMOX1
HMOX2
HTATIP2
IGFBP5
INSIG2
JAGN1
KIR2DL3
LHFPL5
LPAR3
LRP10
MAL
MARCHF2
MFF
MGLL
MIP
MMD
MMD2
MS4A1
MS4A13
MYADM
MYADML2
NAPB
NAT8
NCR3
NINJ2
NRM
NXPE3
OLFM4
ORMDL3
OTOR
PAQR7
PEDS1-UBE2V1
PGAP2
PGLYRP3
PLN
PLP1
PLP2
PLPP4
PLPP6
PMP22
PNLIPRP1
PRB1
PTCH1
RHAG
RPRM
RTP2
RUSF1
S100A2
SCARF1
SCGB1D1
SCRG1
SEC22A
SEC22B
SEC61G
SELENOK
SEMA6C
SERP1
SFTPC
SLC13A3
SLC1A1
SLC30A8
SLC35A1
SLC35A4
SLC35B4
SLC35E3
SLC35G2
SLC38A7
SLC52A2
SLC7A14
SMCO4
SMIM1
SNORC
STATH
STX1B
STX3
STX5
STX8
SYNGR1
SYT15
TECR
TEX264
TFRC
THBD
THSD7B
TM6SF2
TMBIM6
TMEM100
TMEM107
TMEM11
TMEM120A
TMEM128
TMEM140
TMEM141
TMEM14B
TMEM14C
TMEM203
TMEM208
TMEM218
TMEM222
TMEM229B
TMEM236
TMEM243
TMEM254
TMEM42
TMEM43
TMEM47
TMEM50B
TMEM60
TMEM65
TMEM72
TMEM79
TMEM86A
TMEM86B
TMEM97
TMPRSS4
TMUB2
TNF
TNFRSF10C
TNMD
TRAF3IP3
TRAM1L1
TSPAN2
TSPAN33
TSPAN7
TSPO
TWSG1
UBE2J1
UBIAD1
UNC50
UPK1B
VAMP3
VAMP4
VAMP5
VKORC1
VMP1
WFDC2
WFS1
YIPF6
ZFPL1
Entrez ID
1296
200232
HPRD ID
08347
18536
Ensembl ID
ENSG00000171812
ENSG00000124103
Uniprot IDs
E9PP49
P25067
Q5JX71
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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