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COL8A2 and GPR152
Data Source:
BioGRID
(two hybrid)
COL8A2
GPR152
Description
collagen type VIII alpha 2 chain
G protein-coupled receptor 152
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Collagen Trimer
Basement Membrane
Extracellular Space
Endoplasmic Reticulum Lumen
Extracellular Matrix
Collagen-containing Extracellular Matrix
Plasma Membrane
Integral Component Of Membrane
Molecular Function
Extracellular Matrix Structural Constituent
Extracellular Matrix Structural Constituent Conferring Tensile Strength
Protein-macromolecule Adaptor Activity
G Protein-coupled Receptor Activity
Protein Binding
Identical Protein Binding
Biological Process
Angiogenesis
Extracellular Matrix Organization
Camera-type Eye Morphogenesis
Epithelial Cell Proliferation
Cell-cell Adhesion
G Protein-coupled Receptor Signaling Pathway
Pathways
Collagen degradation
Collagen degradation
Collagen biosynthesis and modifying enzymes
Assembly of collagen fibrils and other multimeric structures
Integrin cell surface interactions
Collagen chain trimerization
Drugs
Diseases
Posterior polymorphous corneal dystrophy (PPCD)
Fuchs corneal dystrophy (FECD); Fuchs endothelial corneal dystrophy
GWAS
Central corneal thickness (
32528159
29760442
)
Corneal structure (
23291589
)
Early spontaneous preterm birth (
31194736
)
Intraocular pressure (
29617998
29785010
31959993
)
Non-response to citalopram or escitalopram and depression (
27622933
)
Refractive error (
32231278
)
Interacting Genes
18 interacting genes:
ARL13B
ATP6V0E1
BSND
COL8A1
CREB3L1
CYB5R3
DARS2
FAM209A
FNDC9
GPR152
GPX8
LMNA
MUC1
PEX12
PLEKHO1
SGTA
TFAM
TMX2
194 interacting genes:
-
ABCG4
ABHD16A
ACSF2
ADIPOQ
AGTRAP
AIG1
ANKRD46
APOL3
AQP10
AQP3
AQP6
ARL6IP1
ARV1
ATP6V0C
B3GNT7
BDNF
BET1
BMP10
BNIP2
BNIP3
C14orf180
C1QL4
C8A
CCDC167
CCL4
CCL4L2
CD53
CD72
CD81
CDIPT
CDS2
CGRRF1
CLDND2
CLEC17A
CLEC1A
CLN5
CNIH1
COL8A2
COMT
CRISP3
CSGALNACT2
CTXN3
CYB561
CYB561A3
CYB5B
CYB5R3
CYBC1
DEFB108B
DGAT2L6
EBP
EDDM3B
EFNA5
EMD
ERG28
FA2H
FAM20B
FAXDC2
FDFT1
FUNDC2
FXYD3
FXYD6-FXYD2
GAST
GJB2
GOLT1A
GOLT1B
GOSR2
GPR151
GPR37L1
HHATL
HMOX1
HMOX2
IFNA8
IGF2
IGFBP5
IL1RL1
INS-IGF2
INSIG2
JAGN1
KCNA1
KCNN4
LAMB1
LAT
LEPROTL1
LHFPL2
LHFPL5
LTC4S
MAL
MAL2
MFF
MFSD5
MFSD6
MGLL
MGST3
MMD
MOSPD3
MS4A13
MYADML2
NAT8
NDUFB11
NEU1
NINJ2
NIPAL4
ORMDL1
ORMDL3
PEDS1-UBE2V1
PEX16
PGAP2
PIGF
PIN1
PLN
PNLIPRP1
PRAF2
PROM2
PTPRN
RABAC1
RBFA
REEP6
ROBO2
RTN3
RTP2
SACM1L
SCAMP4
SCD
SEC22B
SERF1A
SERF1B
SERP2
SFT2D2
SFTPC
SLC10A1
SLC13A4
SLC29A2
SLC30A3
SLC35A4
SLC35B1
SLC35B4
SLC35C2
SLC35F6
SLC38A1
SLC38A7
SLC39A2
SLC41A1
SLC66A1
SLC66A2
SLC7A1
SMCO4
STATH
STX1B
STX3
STX4
STX5
STX8
SYT15
TAP1
TEX264
TFRC
THSD7B
TIMMDC1
TM4SF19
TMEM100
TMEM120B
TMEM128
TMEM140
TMEM14B
TMEM14C
TMEM201
TMEM208
TMEM218
TMEM236
TMEM237
TMEM243
TMEM254
TMEM42
TMEM50B
TMEM54
TMEM60
TMEM97
TMPPE
TNFRSF10C
TSNARE1
TSPAN33
TSPAN7
TSPO2
UBIAD1
UNC50
VAMP1
VAMP4
VAMP5
VKORC1
YIPF1
YIPF4
YIPF6
ZDHHC15
Entrez ID
1296
390212
HPRD ID
08347
13599
Ensembl ID
ENSG00000171812
ENSG00000175514
Uniprot IDs
E9PP49
P25067
A0A0I9RJ67
Q8TDT2
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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