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SYT2 and NAPB
Data Source:
BioGRID
(two hybrid)
SYT2
NAPB
Description
synaptotagmin 2
NSF attachment protein beta
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Integral Component Of Membrane
Axon
Clathrin-coated Vesicle Membrane
Synaptic Vesicle Membrane
Dense Core Granule
Chromaffin Granule Membrane
Exocytic Vesicle
Vacuolar Membrane
SNARE Complex
Synapse
Synaptobrevin 2-SNAP-25-syntaxin-1a Complex
Extracellular Exosome
Molecular Function
SNARE Binding
Phosphatidylserine Binding
Calcium Ion Binding
Protein Binding
Calcium-dependent Phospholipid Binding
Syntaxin Binding
Clathrin Binding
Inositol 1,3,4,5 Tetrakisphosphate Binding
Soluble NSF Attachment Protein Activity
Protein Binding
Syntaxin Binding
Biological Process
Regulation Of Dopamine Secretion
Vesicle-mediated Transport
Calcium-ion Regulated Exocytosis
Regulation Of Calcium Ion-dependent Exocytosis
Cell Differentiation
Synaptic Vesicle Endocytosis
Calcium Ion-regulated Exocytosis Of Neurotransmitter
Membrane Organization
Cellular Response To Calcium Ion
Positive Regulation Of Dendrite Extension
Intracellular Protein Transport
Regulation Of Synaptic Vesicle Priming
Synaptic Transmission, Glutamatergic
SNARE Complex Disassembly
Pathways
Toxicity of botulinum toxin type B (botB)
Neurexins and neuroligins
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
COPII-mediated vesicle transport
COPI-mediated anterograde transport
COPI-dependent Golgi-to-ER retrograde traffic
Intra-Golgi traffic
Retrograde transport at the Trans-Golgi-Network
Drugs
Botulinum Toxin Type B
Diseases
GWAS
Celiac disease (
23936387
)
Epilepsy and lamotrigine-induced maculopapular eruptions (
26220383
)
Factor VII activity (
30642921
)
Interacting Genes
29 interacting genes:
AQP10
BNIP2
CCDC167
CLDN4
CMTM3
FA2H
FUNDC2
ITGAM
KLHL3
LAT
MALL
MIP
NAPB
NRXN1
ORMDL3
PLPP4
PMP22
SLC30A8
SLC35A1
SLC35A4
STON2
SYNCRIP
TF
THSD7B
TMEM107
TMEM229B
TSPO2
VAMP4
WNK1
31 interacting genes:
ALOX5AP
ARL6IP1
BET1
CISD2
CLEC10A
CREB3L1
DGAT2L6
FAM209A
GJB5
HSD17B13
KCNN3
LEUTX
PLEKHO1
SDCBP
SIGLEC5
SNAP23
SNAP29
STX16
STX19
STX1A
STX1B
STX2
STX3
STX4
STX5
STX6
SYT1
SYT2
TAF1B
TFEC
TMEM139
Entrez ID
127833
63908
HPRD ID
02520
17627
Ensembl ID
ENSG00000143858
ENSG00000125814
Uniprot IDs
Q8N9I0
A0A087WZQ7
Q9H115
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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