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SYT2 and CLDN4
Data Source:
BioGRID
(two hybrid)
SYT2
CLDN4
Description
synaptotagmin 2
claudin 4
Image
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Integral Component Of Membrane
Axon
Clathrin-coated Vesicle Membrane
Synaptic Vesicle Membrane
Dense Core Granule
Chromaffin Granule Membrane
Exocytic Vesicle
Plasma Membrane
Integral Component Of Plasma Membrane
Cell-cell Junction
Bicellular Tight Junction
Basal Plasma Membrane
Apical Plasma Membrane
Apicolateral Plasma Membrane
Lateral Plasma Membrane
Chloride Channel Complex
Tight Junction
Molecular Function
SNARE Binding
Phosphatidylserine Binding
Calcium Ion Binding
Protein Binding
Calcium-dependent Phospholipid Binding
Syntaxin Binding
Clathrin Binding
Inositol 1,3,4,5 Tetrakisphosphate Binding
Transmembrane Signaling Receptor Activity
Structural Molecule Activity
Chloride Channel Activity
Protein Binding
Identical Protein Binding
Biological Process
Regulation Of Dopamine Secretion
Vesicle-mediated Transport
Calcium-ion Regulated Exocytosis
Regulation Of Calcium Ion-dependent Exocytosis
Cell Differentiation
Synaptic Vesicle Endocytosis
Calcium Ion-regulated Exocytosis Of Neurotransmitter
Membrane Organization
Cellular Response To Calcium Ion
Positive Regulation Of Dendrite Extension
Cell Adhesion
Female Pregnancy
Circadian Rhythm
Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules
Regulation Of Cell Morphogenesis
Positive Regulation Of Cell Migration
Response To Progesterone
Establishment Of Skin Barrier
Renal Absorption
Bicellular Tight Junction Assembly
Positive Regulation Of Wound Healing
Chloride Transmembrane Transport
Positive Regulation Of Metallopeptidase Activity
Pathways
Toxicity of botulinum toxin type B (botB)
Neurexins and neuroligins
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
Tight junction interactions
Drugs
Botulinum Toxin Type B
Diseases
GWAS
Celiac disease (
23936387
)
Epilepsy and lamotrigine-induced maculopapular eruptions (
26220383
)
Interacting Genes
29 interacting genes:
AQP10
BNIP2
CCDC167
CLDN4
CMTM3
FA2H
FUNDC2
ITGAM
KLHL3
LAT
MALL
MIP
NAPB
NRXN1
ORMDL3
PLPP4
PMP22
SLC30A8
SLC35A1
SLC35A4
STON2
SYNCRIP
TF
THSD7B
TMEM107
TMEM229B
TSPO2
VAMP4
WNK1
19 interacting genes:
AQP6
ARL13B
CLEC14A
EPHA2
FAM209A
FFAR2
GJA8
GOLM1
HSD17B13
ICAM3
MFSD14B
SHBG
SYT2
TJP1
TMEM237
TMEM52B
TRIM59
TSPO2
WNK4
Entrez ID
127833
1364
HPRD ID
02520
04218
Ensembl ID
ENSG00000143858
ENSG00000189143
Uniprot IDs
Q8N9I0
O14493
Q75L80
PDB IDs
5B2G
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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