CLNS1A and LSM6

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		CLNS1A	LSM6
Description		chloride nucleotide-sensitive channel 1A	LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Cytoskeleton Plasma Membrane Methylosome PICln-Sm Protein Complex	P-body Nucleus Nucleoplasm U6 SnRNP Nucleolus Sno(s)RNA-containing Ribonucleoprotein Complex Cytoplasm Cytosol Small Nuclear Ribonucleoprotein Complex U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Lsm2-8 Complex
	Molecular Function	RNA Binding Protein Binding	RNA Binding Protein Binding Protein Heterodimerization Activity
	Biological Process	Spliceosomal SnRNP Assembly Chloride Transport Cell Volume Homeostasis	MRNA Splicing, Via Spliceosome MRNA Catabolic Process TRNA Processing RNA Splicing Maturation Of SSU-rRNA Exonucleolytic Catabolism Of Deadenylated MRNA
Pathways		snRNP Assembly	mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease mRNA Splicing - Major Pathway
Drugs			Uridine Uridine monophosphate Citric acid
Diseases
GWAS		Diastolic blood pressure ( 30224653) Platelet distribution width ( 32888494) Tourette syndrome ( 30818990)	Malaria ( 31844061) Systolic blood pressure response to hydrochlorothiazide in hypertension ( 27802415)
Interacting Genes		17 interacting genes: ACTB CSNK2A1 EIF4A2 EPB41 EPB41L3 FRMD7 ITGA2B LSM10 LSM3 LSM6 PRMT5 SNRPB SNRPD1 SNRPD2 SNRPD3 SNRPG WDR77	16 interacting genes: APP CLNS1A LSM1 LSM2 LSM3 LSM5 LSM7 LSM8 MCRS1 PATL1 POLD2 SDCBP SMN1 SNRPD2 SNRPF TARDBP
Entrez ID		1207	11157
HPRD ID		03694	06286
Ensembl ID		ENSG00000074201	ENSG00000164167
Uniprot IDs		E9PJF4 E9PMI6 J3KN38 P54105	P62312
PDB IDs		6V0O	3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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