AGAP1 and SP110

  • Data Source:
  • BioGRID (affinity chromatography technology)

AGAP1

SP110

Description ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 SP110 nuclear body protein
Image No pdb structure No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adult body size ( 32376654)
  • Aspartate aminotransferase levels in non-alcoholic fatty liver disease ( 31311600)
  • Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444)
  • Craniofacial microsomia ( 26853712)
  • Mean corpuscular hemoglobin ( 29403010)
  • Mean corpuscular volume ( 29403010)
  • Menarche (age at onset) ( 23667675)
  • Venlafaxine response in generalised anxiety disorder (responders vs non-responders after 24 weeks) ( 28437668)
  • B-cell malignancies (chronic lymphocytic leukemia, Hodgkin lymphoma or multiple myeloma) (pleiotropy) ( 28112199)
  • Cholangiocarcinoma in primary sclerosing cholangitis (time to event) ( 28779025)
  • Chronic lymphocytic leukemia ( 18758461 28165464 24292274)
  • Crohn's disease ( 28067908)
  • Inflammatory bowel disease ( 28067908)
  • Obesity-related traits ( 23251661)
  • Subcutaneous adipose tissue ( 26480920)
Interacting Genes 14 interacting genes: APP ARF1 ARF6 CDC42 GRB7 GUCY1A1 GUCY1B1 RAC1 RHOA RSPH14 SMN1 SRC TK1 ZNF534 11 interacting genes: ANXA7 CDKN1A NAP1L2 NDUFV2 OSGEP RUNX3 SMN1 TK1 TSC22D1 TTR ZSCAN9
Entrez ID 116987 3431
HPRD ID 16359 06832
Ensembl ID ENSG00000157985 ENSG00000135899
Uniprot IDs B2RZG9 Q9UPQ3 X5D293 Q9HB58
PDB IDs
Enriched GO Terms of Interacting Partners?
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