PGLYRP3 and HSD17B14

Data Source:
BioGRID (two hybrid)

		PGLYRP3	HSD17B14
Description		peptidoglycan recognition protein 3	hydroxysteroid 17-beta dehydrogenase 14
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GO Annotations	Cellular Component	Extracellular Region Membrane Protein-containing Complex	Cytosol
	Molecular Function	Protein Binding Zinc Ion Binding N-acetylmuramoyl-L-alanine Amidase Activity Peptidoglycan Immune Receptor Activity Peptidoglycan Binding Protein Heterodimerization Activity	Estradiol 17-beta-dehydrogenase Activity Protein Binding Identical Protein Binding Testosterone 17-beta-dehydrogenase (NADP+) Activity
	Biological Process	Peptidoglycan Catabolic Process Detection Of Bacterium Antimicrobial Humoral Response Killing Of Cells Of Other Organism Negative Regulation Of Interferon-gamma Production Negative Regulation Of Natural Killer Cell Differentiation Involved In Immune Response Innate Immune Response Defense Response To Gram-positive Bacterium Biological Process Involved In Interaction With Host Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide	Estrogen Biosynthetic Process Steroid Catabolic Process
Pathways		Antimicrobial peptides	Estrogen biosynthesis
Drugs		2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSE(BETA1-4)-2-ACETAMIDO-1,6-ANHYDRO-3-O-[(R)-1-CARBOXYETHYL]-2-DEOXY-BETA-D-GLUCOPYRANOSE-L-ALANYL-GAMMA-D-GLUTAMYL-MESO-DIAMINOPIMELYL-D-ALANINE
Diseases
GWAS		Asthma ( 31619474)	Blood protein levels ( 30072576) Resting metabolic rate ( 28476931)
Interacting Genes		4 interacting genes: CIDEB FAM209A HSD17B14 KRT34	24 interacting genes: AKIRIN2 BRIP1 CA8 CDKN2D CYTOR DDIT3 INCA1 MIA3 MIR4435-2HG MPG NEK6 NTAQ1 NUDT18 OTUD3 PGLYRP3 PHF1 PICK1 PIDD1 PSMA1 REL SNAPC3 SNRPC SREK1IP1 TBC1D22B
Entrez ID		114771	51171
HPRD ID		16297	16801
Ensembl ID		ENSG00000159527	ENSG00000087076
Uniprot IDs		Q96LB9	A0A140VJH8 Q9BPX1
PDB IDs		1SK3 1SK4 1TWQ 2APH	1YDE 5EN4 5HS6 5ICM 5ICS 5JS6 5JSF 5L7T 5L7W 5L7Y 5O42 5O43 5O6O 5O6X 5O6Z 5O72 5O7C 6EMM 6FFB 6G4L 6GBT 6GTB 6GTU 6H0M 6HNO 6QCK
Enriched GO Terms of Interacting Partners?
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