TMEM106C and CLDN19

Data Source:
BioGRID (two hybrid)

		TMEM106C	CLDN19
Description		transmembrane protein 106C	claudin 19
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Endoplasmic Reticulum Membrane Integral Component Of Membrane	Nucleus Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane Basolateral Plasma Membrane Apical Junction Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Molecular_function Protein Binding	Structural Molecule Activity Identical Protein Binding
	Biological Process	Biological_process	Positive Regulation Of Protein Phosphorylation Cell Adhesion Visual Perception Negative Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Neuronal Action Potential Propagation Negative Regulation Of Cell Migration Actin Cytoskeleton Reorganization Response To Stimulus Negative Regulation Of Wound Healing Bicellular Tight Junction Assembly Regulation Of Transepithelial Transport Positive Regulation Of Cell Junction Assembly
Pathways			Tight junction interactions
Drugs
Diseases
GWAS		Lymphocyte percentage of white cells ( 32888494) Metabolite levels ( 23823483)
Interacting Genes		42 interacting genes: ADAM33 AIG1 BNIP3 C14orf180 CLDN19 CMTM7 CTXN3 CXCL9 EDDM3B FAXDC2 GOSR2 HACD1 IGFBP5 JAGN1 KRT31 KRTAP10-3 MAL MARCHF2 MYADM NKG7 NRSN1 PGA4 PLN PLP1 PLPP6 PTTG1IP RPRM SEC22A SERP2 SFTPC SMAGP TMEM106A TMEM106B TMEM11 TMEM218 TMEM35A TMEM97 TSPAN33 UPK2 VAMP5 YIPF6 ZFPL1	63 interacting genes: AQP6 AQP9 BCL2L13 BIK BSCL2 BTN2A1 CD200R1 CD53 CD74 CLEC14A CLEC2D CLRN1 CREB3 CXCR3 CYSRT1 ERGIC3 FAM209A FCGR1A FCGRT FKBP7 FNDC9 GGT7 GJA8 GORAB GPR161 GPX8 HSD17B13 ICAM3 IFNGR2 IL3RA KEL KIR2DL3 KRT31 KRT34 LAPTM5 LRRC25 LRRC4C MFF MS4A14 MS4A4A MUC1 PDZK1IP1 PKD2L1 PLEKHB2 PVR SAR1A SCARB2 SGPL1 SLAMF6 SLC10A1 SLC35C2 SPACA1 SRPK2 STOM STOML3 SUSD3 SYNE4 TM4SF18 TMEM106C TMEM248 TMEM52B TMEM80 TNFSF14
Entrez ID		79022	149461
HPRD ID		14690	10834
Ensembl ID		ENSG00000134291	ENSG00000164007
Uniprot IDs		Q9BVX2	Q8N6F1
PDB IDs
Enriched GO Terms of Interacting Partners?
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